Most Read Articles
Stephen Padilla, 21 Apr 2021
People who are physically active are less likely to progress to severe COVID-19 if diagnosed with the disease as opposed to their physically inactive counterparts, suggests a recent study.
Tristan Manalac, 18 Mar 2021
Both daily and on-demand regimens of pre-exposure prophylaxis (PrEP) with tenofovir/emtricitabine (TDF/FTC) strongly suppress the rates of HIV infection among men who have sex with men (MSM), according to a study presented at the 2021 Conference on Retroviruses and Opportunistic Infections (CROI 2021).
Stephen Padilla, 18 Mar 2021
Sex appears to have a strong influence on many discrete pathways of inflammation that independently predict cardiovascular disease (CVD) and venous thromboembolism (VTE) events in patients with HIV on antiretroviral therapy (ART), according to a study presented at the Conference on Retroviruses and Opportunistic Infections 2021.
02 May 2021
Vaccination against SARS-CoV-2 does not seem to come with significant safety concerns in patients with nonalcoholic fatty liver disease (NAFLD), a recent study has found. At the same time, vaccines can also elicit a robust neutralizing antibody response.

Blood glucose, HbA1c not linked to infection rates after penile prosthesis implantation

30 Apr 2021

Blood glucose and haemoglobin A1c (HbA1c) levels before penile prosthesis (PP) placement do not seem to influence the risk of postoperative infection, revision, or explantation among diabetic men, a recent study has found.

Researchers retrospectively reviewed 932 diabetic men scheduled for primary penile prosthesis implantation. The primary outcome was postoperative infection, while secondary outcomes were revisions and explantations. These were assessed in light of HbA1c and blood glucose levels measured within 6 hours before the surgery.

Overall, 3.8 percent of the participants experienced postoperative infections, while revisions and explantations were performed in 7.1 percent and 4.2 percent, respectively. Average preoperative blood glucose and HbA1c levels were 148.5±49.6 mg/dL and 7.5±1.5 percent, respectively.

Neither preoperative blood glucose (p=0.220) nor HbA1c (p=0.596) levels were significantly correlated with postoperative infection rates. Revision (p=0.332 and p=0.104, respectively) and explantation (p=0.806 and p=0.662, respectively) were also unrelated to the preoperative blood markers.

Multivariate logistic regression analysis further confirmed that postoperative blood glucose (B, 0.994, 95 percent confidence interval [CI], 0.984–1.005) and HbA1c (B, 1.052, 95 percent CI, 0.766–1.443) had no significant interactions with postoperative infections.

The same was true for explantation (blood glucose: B, 0.999, 95 percent CI, 0.989–1.008; HbA1c: B, 1.083, 95 percent CI, 0.789–1.485) and revision (blood glucose: B, 0.991, 95 percent CI, 0.981–1.001; HbA1c: B, 1.179, 95 percent CI, 0.916–1.517).

“In the future, studies should look at different predictors of postoperative complications in diabetic men undergoing PP implantation,” the researchers said.

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Most Read Articles
Stephen Padilla, 21 Apr 2021
People who are physically active are less likely to progress to severe COVID-19 if diagnosed with the disease as opposed to their physically inactive counterparts, suggests a recent study.
Tristan Manalac, 18 Mar 2021
Both daily and on-demand regimens of pre-exposure prophylaxis (PrEP) with tenofovir/emtricitabine (TDF/FTC) strongly suppress the rates of HIV infection among men who have sex with men (MSM), according to a study presented at the 2021 Conference on Retroviruses and Opportunistic Infections (CROI 2021).
Stephen Padilla, 18 Mar 2021
Sex appears to have a strong influence on many discrete pathways of inflammation that independently predict cardiovascular disease (CVD) and venous thromboembolism (VTE) events in patients with HIV on antiretroviral therapy (ART), according to a study presented at the Conference on Retroviruses and Opportunistic Infections 2021.
02 May 2021
Vaccination against SARS-CoV-2 does not seem to come with significant safety concerns in patients with nonalcoholic fatty liver disease (NAFLD), a recent study has found. At the same time, vaccines can also elicit a robust neutralizing antibody response.