Most Read Articles
26 Jun 2020

Achieving standard of care targets, such as reduced levels of low-density lipoprotein cholesterol and glycated haemoglobin, improves outcomes in coronary heart disease patients, a new study has found.

Pearl Toh, 19 Jan 2018
Blood pressure (BP) control can be best achieved with a multilevel, multicomponent approach involving team-based care with physician- and non-physician-led interventions, as well as patient-level strategies, according to findings of a meta-analysis.
Dr. Joseph Delano Fule Robles, 24 Jul 2018

Functional foods benefit the body beyond its nutritional effects, with studies showing that they can improve general state of health and reduce the risk of diseases.

29 Mar 2020
Targeting a low-density lipoprotein cholesterol level <70 mg/dL following an ischaemic stroke of atherosclerotic origin helps to avoid one in four subsequent major vascular events without increasing the risk of intracranial haemorrhage over about 5 years of follow-up, according to data from the Treat Stroke to Target trial.

Bleeding risk high for percutaneous coronary intervention patients

28 May 2020

Patients undergoing percutaneous coronary intervention (PCI) are generally at risk of bleeding complications, which prolonged courses of dual antiplatelet therapy (DAPT) could aggravate, a recent study has found.

The study included 7,499 PCI patients, of whom 3,550 had high-bleeding-risk (HBR) features, such as old age, anticoagulation use at discharge, and a prior history of stroke, among other such factors. The remaining 3,949 patients had low-bleeding-risk (LBR) features. In-hospital and follow-up complications, such as major bleeding and death, were the study outcomes.

At baseline, the DAPT score was significantly higher in the HBR patients than in their LBR counterparts (3.7±1.4 vs 2.96±1.1; p<0.001).

Comparing both risk groups, researchers found that the likelihood of vascular complications (3.1 percent vs 1.5 percent; p<0.001) and needing transfusions (5 percent vs 1.6 percent; p<0.001) while admitted were both significantly higher in the HBR group.

During follow-up, the risk of 30-day major bleeding (1.4 percent vs 0.5 percent; p=0.001), and of 6-month death (1.9 percent vs 0.2 percent), major bleeding (6.3 percent vs 2.1 percent; p<0.001 for both), and target lesion revascularization (3.2 percent vs 2.2 percent; p=0.008) were all significantly higher in HBR patients.

The same was true for death and major bleeding at the 12-month (4.4 percent vs 0.6 percent and 10.3 percent vs 4.2 percent, respectively; p<0.001 for both) and 24-month (10 percent vs 1.7 percent and 16.4 percent and 7.1 percent, respectively; p<0.001 for both) follow-ups.

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Most Read Articles
26 Jun 2020

Achieving standard of care targets, such as reduced levels of low-density lipoprotein cholesterol and glycated haemoglobin, improves outcomes in coronary heart disease patients, a new study has found.

Pearl Toh, 19 Jan 2018
Blood pressure (BP) control can be best achieved with a multilevel, multicomponent approach involving team-based care with physician- and non-physician-led interventions, as well as patient-level strategies, according to findings of a meta-analysis.
Dr. Joseph Delano Fule Robles, 24 Jul 2018

Functional foods benefit the body beyond its nutritional effects, with studies showing that they can improve general state of health and reduce the risk of diseases.

29 Mar 2020
Targeting a low-density lipoprotein cholesterol level <70 mg/dL following an ischaemic stroke of atherosclerotic origin helps to avoid one in four subsequent major vascular events without increasing the risk of intracranial haemorrhage over about 5 years of follow-up, according to data from the Treat Stroke to Target trial.