Most Read Articles
5 days ago
Routinely used for treating cardiovascular diseases, statins have been shown to benefit other conditions, and new evidence suggests that using the drug at high intensity reduces the risk of hip or knee replacement, an effect that may be specific to rheumatoid arthritis.
Jairia Dela Cruz, 6 days ago
Following vegan and vegetarian diets, which offer plenty of what is good for health, has been reported to have a downside: an increased risk of depression and anxiety, especially for younger adults.
Pearl Toh, 29 Jun 2020
Having migraine during midlife appears to be associated with a higher risk of developing dementia in later life, according to a large population-based longitudinal Danish study presented at the AHS* 2020 Virtual Meeting, indicating that migraine may be a risk factor for dementia.
Roshini Claire Anthony, 3 days ago

Upadacitinib may be a suitable treatment for patients with active psoriatic arthritis (PsA) who have insufficient response to non-biologic disease-modifying anti-rheumatic drugs (non-bDMARDs), according to results of the phase III SELECT-PsA-1* trial presented at EULAR 2020.

Bioresorbable scaffolds, drug eluting stents perform comparably for long coronary lesions

31 May 2020

Bioresorbable vascular scaffolds (BVSs) and everolimus-eluting stents (EESs) show similar performance in patients with long native coronary artery disease, a recent study has found.

A total of 341 patients with diffuse long lesions were randomly assigned to receive either BVS (n=171) or EES (n=170) implants. Participants were scheduled to be followed up for 12 months, during which the development of major adverse cardiovascular events (MACEs)―such as cardiac deaths, myocardial infarction, device thrombosis and ischaemia-driven target-lesion revascularization―was observed.

The mean lesion length was 32.2±13.1 mm in the BVS arm and 35.3±13.0 mm in the EES arm. All enrolled patients needed a device that was at least 28 mm in length.

A total of 332 patients (97.4 percent) were able to finish clinical follow-up at 12 months. In these patients, the primary composite endpoint of MACEs occurred in two participants in the BVS arm and in four patients in the EES arm. The resulting incidence rates were 1.2 percent and 2.4 percent.

This led to a statistically similar risk estimate between treatment groups (hazard ratio, 0.49, 95 percent confidence interval, 0.09–2.67; p=0.398). This trend remained true even in the individual components of MACE. In particular, only one patient from each group experienced device thrombosis.

However, the researchers pointed out that because the manufacturer stopped supplying BVS, recruitment for the trial had to be terminated early. “Therefore, this report provides descriptive information on endpoint events without formal hypothesis testing,” and the results cannot be considered clinically relevant.

Digital Edition
Asia's trusted medical magazine for healthcare professionals. Get your MIMS Doctor - Malaysia digital copy today!
Sign In To Download
Editor's Recommendations
Most Read Articles
5 days ago
Routinely used for treating cardiovascular diseases, statins have been shown to benefit other conditions, and new evidence suggests that using the drug at high intensity reduces the risk of hip or knee replacement, an effect that may be specific to rheumatoid arthritis.
Jairia Dela Cruz, 6 days ago
Following vegan and vegetarian diets, which offer plenty of what is good for health, has been reported to have a downside: an increased risk of depression and anxiety, especially for younger adults.
Pearl Toh, 29 Jun 2020
Having migraine during midlife appears to be associated with a higher risk of developing dementia in later life, according to a large population-based longitudinal Danish study presented at the AHS* 2020 Virtual Meeting, indicating that migraine may be a risk factor for dementia.
Roshini Claire Anthony, 3 days ago

Upadacitinib may be a suitable treatment for patients with active psoriatic arthritis (PsA) who have insufficient response to non-biologic disease-modifying anti-rheumatic drugs (non-bDMARDs), according to results of the phase III SELECT-PsA-1* trial presented at EULAR 2020.