Most Read Articles
Pearl Toh, 20 Nov 2019
The trade-off between the risk of ischaemic vs bleeding events may be different between Asian and non-Asian patients, which warrants careful consideration when deciding on the duration of antiplatelet therapy following a percutaneous coronary intervention (PCI), according to a presentation at ESC Asia Congress 2019.
4 days ago
Participating in a long-distance skiing event may help lower the risk of hypertension, with the number of completed races showing a weak association with the risk, a study has found.
06 Sep 2019
Hypertensive adults with lower plasma zinc concentration are at increased risk of haemorrhagic stroke, especially those with higher body mass index or lower plasma copper levels, a study has found.
06 Jan 2020
Target organ damage appears to be more noticeable in patients affected by primary aldosteronism than those affected by arterial hypertension without primary aldosteronism, suggests a study, adding that specific treatment can ease such condition.

Binge drinking ups risk of arterial stiffness in young adults

5 days ago

Young adults who repeatedly binge-drink alcohol, irrespective of drinking pattern, are at higher risk of aortic arterial stiffness, according to a study. Moreover, sympathetic activation as shown by increased 24-h urinary norepinephrine levels may contribute to alcohol-induced arterial stiffening in this cohort.

This study sought to determine the effect of repeated binge drinking and moderate alcohol consumption on arterial stiffness and sympathetic activity in healthy young adults.

Forty-nine young adults free of cardiovascular diseases (mean age, 23.5 years; 25 men; mean body mass index, 23.4 kg/m2) were included in the analysis. Participants were categorized as repeated binge drinkers (>2 years duration; n=20), moderate drinkers (>5 years duration; n=16) and alcohol abstainers (last 2–3 years; n=13).

The authors evaluated arterial stiffness using cfPWV and sympathetic activity using 24-h urinary norepinephrine levels. They also measured the aortic systolic blood pressure and augmentation index, a measure of wave reflection.

Carotid to femoral pulse wave velocity (cfPWV) was higher among binge drinkers (0.6 m/s) and moderate drinkers (0.5 m/s) than alcohol abstainers (p≤0.04). Binge drinkers also had higher urinary norepinephrine levels compared to moderate drinkers and alcohol abstainers (p<0.05). Moreover, higher cfPWV was associated with higher norepinephrine levels (r, 0.35; p=0.02).

Aortic systolic blood pressure (p=0.2) and augmentation index (p=0.96) were comparable among binge drinkers, moderate drinkers and alcohol abstainers.

Digital Edition
Asia's trusted medical magazine for healthcare professionals. Get your MIMS Cardiology - Malaysia digital copy today!
Sign In To Download
Editor's Recommendations
Most Read Articles
Pearl Toh, 20 Nov 2019
The trade-off between the risk of ischaemic vs bleeding events may be different between Asian and non-Asian patients, which warrants careful consideration when deciding on the duration of antiplatelet therapy following a percutaneous coronary intervention (PCI), according to a presentation at ESC Asia Congress 2019.
4 days ago
Participating in a long-distance skiing event may help lower the risk of hypertension, with the number of completed races showing a weak association with the risk, a study has found.
06 Sep 2019
Hypertensive adults with lower plasma zinc concentration are at increased risk of haemorrhagic stroke, especially those with higher body mass index or lower plasma copper levels, a study has found.
06 Jan 2020
Target organ damage appears to be more noticeable in patients affected by primary aldosteronism than those affected by arterial hypertension without primary aldosteronism, suggests a study, adding that specific treatment can ease such condition.