Most Read Articles
Rachel Soon, 3 days ago

Gels utilizing Stichopus horrens (golden sea cucumber/gamat) extract show a similar efficacy to standard-of-care hydrogels for promoting wound healing, according to a prospective study.

16 Mar 2019
Sleep difficulties are exacerbated in long-term survivors of childhood cancers, which may lead to persistent emotional distress, a new study has found.
2 days ago
Higher cancer symptom burden in elderly adults is associated with functional impairment, reports a recent study.
Jairia Dela Cruz, 5 days ago
Use of mirabegron in the treatment of men with overactive bladder (OAB) appears to effectively alleviate urgency and storage symptoms, but not reduce the frequency of micturition episodes, according to data from the MIRACLE study.

Better cardiovascular health tied to lower risk of nonalcoholic fatty liver disease

02 Jan 2019

Increasing cardiovascular health is associated with a lower risk of nonalcoholic fatty liver disease (NAFLD), a new study has shown.

Researchers followed 3,424 adults (mean age 57.3±8.8 years; 73.9 percent female) with no baseline NAFLD for 5 years for the development of the disease. Cardiovascular health metrics included smoking, body mass index (BMI) blood pressure, total cholesterol, fasting glucose and physical activity.

A total of 649 participants (19.0 percent) developed NAFLD, among whom unfavourable baseline metabolic risk profiles were more common. For instance, only 41.5 percent of these participants had ideal baseline BMI, as opposed to 67.4 percent in the group who did not develop NAFLD (p<0.01).

After adjusting for sociodemographic variables, lifestyle behaviours and clinical factors, having ideal BMI at baseline was associated with a significantly lower risk of NAFLD development (odds ratio [OR], 0.40; 95 percent CI, 0.33–0.48). Ideal blood pressure at baseline had the same effect (OR, 0.73; 0.55–0.98).

Moreover, NAFLD risk progressively dropped as the number of ideal cardiovascular metrics at baseline increased (reference: 0–2 ideal metrics; 3–4 metrics: OR, 0.50; 0.41–0.61; 5–6 metrics: OR, 0.34; 0.22–0.51).

At the 5-year follow-up, cardiovascular health deteriorated in 1,373 participants, such that the mean number of ideal metrics dropped from 3.56±1.01 at baseline to 2.23±0.95 at follow-up. Compared to these patients, those whose cardiovascular health was stable (n=1,170; OR, 0.61; 0.49–0.76) or improved (OR, 0.29; 0.21–0.39) showed significantly lower risks of NAFLD development.

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Most Read Articles
Rachel Soon, 3 days ago

Gels utilizing Stichopus horrens (golden sea cucumber/gamat) extract show a similar efficacy to standard-of-care hydrogels for promoting wound healing, according to a prospective study.

16 Mar 2019
Sleep difficulties are exacerbated in long-term survivors of childhood cancers, which may lead to persistent emotional distress, a new study has found.
2 days ago
Higher cancer symptom burden in elderly adults is associated with functional impairment, reports a recent study.
Jairia Dela Cruz, 5 days ago
Use of mirabegron in the treatment of men with overactive bladder (OAB) appears to effectively alleviate urgency and storage symptoms, but not reduce the frequency of micturition episodes, according to data from the MIRACLE study.