Most Read Articles
15 Jan 2018
Body surface area (BSA) affected by psoriasis can be measured to target diabetes prevention efforts for patients with psoriasis, a recent study suggests.
Pearl Toh, 14 Apr 2018
Taking the oral extract product of the fern Polypodium leucotomos (PLE) on top of the standard topical hydroquinone cream and sunscreen reduces the severity of melasma to a greater extent compared with the standard treatment alone in Asian patients, a pilot study has shown.
Jan Welch, 01 Jun 2011

Sexually transmitted infections (STIs) are common, with rates of many infections increas­ing over the last two decades.1 Community screening studies in the UK have shown a prevalence of about 10% for chlamydial infection2 and (among women screened in an urban setting) 3% for gonorrhoea.3 In women (Figure 1), these potentially serious infections are often asymptomatic, whereas the presence of symptoms such as vaginal discharge generally indicates a less pathogenic (but still potentially debilitating) infection, with an organism such as Candida. STIs are often multiple, and the finding of one infection should prompt consider­ation of testing for others. Many sexual health services now initially provide screening tests for asymptomatic women, but a more comprehensive assessment—comprising detailed history4 and genital examination5—is usually necessary when symptoms are present.

Stephen Padilla, 5 days ago
High use of hydrochlorothiazide (HCTZ) appears to significantly increase the risk of nonmelanoma skin cancer (NMSC), particularly squamous cell carcinoma (SCC), suggests a recent study. Use of other diuretic and antihypertensive medications does not appear to be linked to NMSC.

Behçet disease ups risk for overall cancer

26 Feb 2018

Patients with Behçet disease (BD) are at an increased risk for overall cancer compared with those without BD, suggests a recent study.

During the follow-up period, cancer was diagnosed in 451 (3.19 percent) patients with BD and 3,975 (2.81 percent) controls.

Compared with controls, patients with BD had significantly higher risk for cancer (hazard ratio [HR], 1.134; 95 percent CI, 1.029–1.25), leukaemia (HR, 5.801; 3.24–10.385), lymphoma (HR, 2.584; 1.5594.283), oral cavity and pharyngeal cancer (HR, 2.113; 1.102–4.052), thyroid cancer (HR, 1.256; 1.05–1.501) and prostate cancer (HR, 1.784; 1.141–2.791).

“Physicians should carefully monitor patients with BD for the potential development of malignancies,” the investigators said.

In this study that sought to determine overall cancer risk and risk for specific cancers in patients with BD, the investigators selected 14,137 participants (mean age 44.2 years; 32.4 percent males) without known previous cancer from the Korean National Health Insurance Database between 2007 and 2014. These patients were matched 1:10 by age and sex to a control population of individuals without BD. Both cohorts were followed for incident cancer until 2015.

One limitation of the study was that treatment or severity of diseases in each individual was not examined, according to the investigators.

In another Korea study using National Health Insurance claims records of 2,402 patients diagnosed with BD between 2013 and 2014, researchers also found that those with BD had higher risks of overall cancer, as well as some solid cancer and myelodysplastic syndrome, but not haematological cancer compared with the general population. [PLoS One 2017;12:e0190182]

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Most Read Articles
15 Jan 2018
Body surface area (BSA) affected by psoriasis can be measured to target diabetes prevention efforts for patients with psoriasis, a recent study suggests.
Pearl Toh, 14 Apr 2018
Taking the oral extract product of the fern Polypodium leucotomos (PLE) on top of the standard topical hydroquinone cream and sunscreen reduces the severity of melasma to a greater extent compared with the standard treatment alone in Asian patients, a pilot study has shown.
Jan Welch, 01 Jun 2011

Sexually transmitted infections (STIs) are common, with rates of many infections increas­ing over the last two decades.1 Community screening studies in the UK have shown a prevalence of about 10% for chlamydial infection2 and (among women screened in an urban setting) 3% for gonorrhoea.3 In women (Figure 1), these potentially serious infections are often asymptomatic, whereas the presence of symptoms such as vaginal discharge generally indicates a less pathogenic (but still potentially debilitating) infection, with an organism such as Candida. STIs are often multiple, and the finding of one infection should prompt consider­ation of testing for others. Many sexual health services now initially provide screening tests for asymptomatic women, but a more comprehensive assessment—comprising detailed history4 and genital examination5—is usually necessary when symptoms are present.

Stephen Padilla, 5 days ago
High use of hydrochlorothiazide (HCTZ) appears to significantly increase the risk of nonmelanoma skin cancer (NMSC), particularly squamous cell carcinoma (SCC), suggests a recent study. Use of other diuretic and antihypertensive medications does not appear to be linked to NMSC.