BEEMS effective in improving balance, fatigue, dizziness in patients with multiple sclerosis
Multifaceted vestibular-related rehabilitation programmes appear to improve balance, fatigue and dizziness in patients with multiple sclerosis (MS), regardless of lesion involvement, a recent study has shown.
Researchers randomized 88 adult MS patients to receive either the Balance and Eye-Movement Exercises for Persons with MS intervention (BEEMS; n=44) or no treatment control (n=44).
Balance in the BEEMS group significantly improved from baseline to 6 weeks, as per the Computerized Dynamic Posturography-Sensory Organization Test (CDP-SOT) composite score (model-estimated difference in change, 4.89; 95 percent CI, 1.39–8.38; p=0.006).
Composite CPD-SOT scores also showed significantly better improvements among BEEMS participants vs controls at 14 weeks (model-estimated difference in change, 8.32; 4.73–11.9; p<0.0001).
In comparison, the reduction in scores in the Dizziness Handicap Index was significantly greater for patients who received BEEMS vs the control intervention both at 6 (model-estimated difference in change, –13.5; –17.7 to –7.25; p<0.0001) and 14 weeks (model-estimated difference in change, –13.9; –19.3 to –8.62; p<0.0001).
Fatigue was also significantly improved in the BEEMS group, showing significantly greater decreases in the Modified Fatigue Impact Scale (MFIS) at 6 (model-estimated difference in change, –11.4; –15.7 to –7.0; p<0.0001) and 14 weeks (model-estimated difference in change, –12.3; –16.7 to –7.79; p<0.0001) compared with the control group.
Notably, those with brainstem/cerebellar lesion involvements experienced significantly greater improvements vs those without in the CDPT-SOT composite (p=0.04) and MFIS (p=0.02) scores.