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Roshini Claire Anthony, 3 days ago

The combined use of piperacillin and tazobactam does not appear to be a suitable alternative to meropenem for patients with bloodstream infections caused by ceftriaxone-resistant Escherichia coli (E. coli) or Klebsiella pneumoniae (K. pneumoniae), according to results of the MERINO* trial.

Tristan Manalac, 19 May 2018
Taking oral antibiotics appears to increase the risk of nephrolithiasis, according to a recent study. Moreover, the risk seems to be compounded for individuals with recent antibiotic exposure and those who were exposed at a younger age.
2 days ago
Patients with inflammatory bowel disease are at increased risk of developing acute myocardial infarction (AMI) or heart failure, although the prevalence of traditional risk factors for such cardiovascular disorders appears to be low, as reported in a recent study.
3 days ago
Early renin-angiotensin-aldosterone system (RAAS) blockade with renin-angiotensin system inhibitors (RASI) leads to better short- and long-term renal outcomes in systemic lupus erythematosus (SLE) patients with antiphospholipid-associated nephropathy (aPLN), according to a study, adding that this renal protective effect is independent of RASI’s antihypertensive and antiproteinuric effects.

Balloon angioplasty better than stenting in renal artery interventions

20 Aug 2017

Balloon angioplasty provides better outcomes in renal artery interventions compared with stent implantation, according to a recent meta-analysis.

Seven studies included a total of 266 patients and 316 lesions, of which 186 were treated with balloon angioplasty while 130 were treated with stenting.  Subsequent meta-analysis showed that there was no significant difference in the incidence of restenosis between the two treatments (odds ratio [OR], 2.39; 0.66 to 8.66; p=0.18).

Similarly, there was no significant difference between the two treatments in terms of improving renal hypertension (OR, 0.65; 0.28 to 1.51; p=0.31).

Balloon angioplasty and stent implantation also conferred similar incidence rates of complications, including progressive renal insufficiency, transient ischaemic attack, stroke and congestive heart failure (OR, 1.80; 0.49 to 6.65; p=0.38).

On the other hand, stenting in renal arteries resulted in higher incidence rates of restenosis compared with balloon angioplasty (OR, 4.40; 2.14 to 9.02; p<0.001). Balloon angioplasty also delivered significantly lower rates of acute vascular complications in renal artery intervention than stenting (OR, 0.07; 0.02 to 0.29; p<0.001).

Studies that compared endovascular balloon angioplasty to stent implantation in Takayasu arteritis patients were searched from the databases of Medline and Embase. Those with unreliable or overlapping data, case reports and reviews were excluded.

Among the information extracted were characteristics of the study sample, number of lesions, location of lesions and treatment method used. Heterogeneity between studies was evaluated using the Cochrane Q test.

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Most Read Articles
Roshini Claire Anthony, 3 days ago

The combined use of piperacillin and tazobactam does not appear to be a suitable alternative to meropenem for patients with bloodstream infections caused by ceftriaxone-resistant Escherichia coli (E. coli) or Klebsiella pneumoniae (K. pneumoniae), according to results of the MERINO* trial.

Tristan Manalac, 19 May 2018
Taking oral antibiotics appears to increase the risk of nephrolithiasis, according to a recent study. Moreover, the risk seems to be compounded for individuals with recent antibiotic exposure and those who were exposed at a younger age.
2 days ago
Patients with inflammatory bowel disease are at increased risk of developing acute myocardial infarction (AMI) or heart failure, although the prevalence of traditional risk factors for such cardiovascular disorders appears to be low, as reported in a recent study.
3 days ago
Early renin-angiotensin-aldosterone system (RAAS) blockade with renin-angiotensin system inhibitors (RASI) leads to better short- and long-term renal outcomes in systemic lupus erythematosus (SLE) patients with antiphospholipid-associated nephropathy (aPLN), according to a study, adding that this renal protective effect is independent of RASI’s antihypertensive and antiproteinuric effects.