Most Read Articles
Stephen Padilla, 23 Nov 2020
Fetoscopic laser ablation (FLP) is an effective treatment for twin-to-twin transfusion syndrome (TTTS) in monochorionic twin pregnancies, but it requires a tertiary neonatal facility and a highly specialized team in performing intervention therapies for the treatment of potential complications, according to a Singapore study.
18 Nov 2020
Serum folate levels during pregnancy correlate with the child’s neurodevelopment at 2 years of age, particularly in terms of language development, a recent study has shown. Folate supplementation may be a valuable nutritional intervention to consider.
18 Oct 2020
Girls with higher body fat percentage and whose parents smoke are likely to undergo precocious puberty, as reported in a study.

Atropine keeps myopia at bay in kids

27 Oct 2020
The prevalence rate of myopia amongst preschool children in Hong Kong has tripled from 2.3% to 6.3% in ten years between 1996 and 2006.

High-dose atropine helps slow the progression of high myopia in kids with or at risk of developing the condition, a recent study has found.

Researchers conducted a prospective clinical effectiveness study on 124 children (median age, 9.5 years; 54 percent female) with myopia (≤–2.5 D) or progressive myopia (≥1 D per year). Atropine was given at a 0.5% concentration, and target outcomes included spherical equivalent (SER) and axial length (AL).

The median SER 1 year before the study was –3.88 D, which worsened to –5.03 D by baseline. This indicated a progression of more than 1 D before treatment. More than a third (37.1 percent) of participants had high myopia (SER ≤–6 D), and the median AL was 25.14 mm.

Eighty-nine children (71.8 percent) stated on-treatment over the 3 years of follow-up. Of these, 34.8 percent (n=31) remained on the 0.5% dose, while 36.0 percent (n=32) and 29.2 percent (n=26) saw an increase and decrease in dose, respectively. No AL rebound was reported after dose reduction.

The median annual progression of SER in patients who completed treatment was –0.25 D, while AL increased at a median rate of 0.11 mm per year. On a per-year basis, researchers saw that the progression of SER dropped to 0.00 D in year 1, –0.41 D in year 2, and –0.38 D in year 3. Relative to before treatment, these corresponded to reduction rates of 100 percent, 65 percent, and 68.2 percent (p<0.01 for all).

For those who dropped out, the most common reasons for termination were allergic reactions, photophobia, and non-eye-related adverse events.

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Most Read Articles
Stephen Padilla, 23 Nov 2020
Fetoscopic laser ablation (FLP) is an effective treatment for twin-to-twin transfusion syndrome (TTTS) in monochorionic twin pregnancies, but it requires a tertiary neonatal facility and a highly specialized team in performing intervention therapies for the treatment of potential complications, according to a Singapore study.
18 Nov 2020
Serum folate levels during pregnancy correlate with the child’s neurodevelopment at 2 years of age, particularly in terms of language development, a recent study has shown. Folate supplementation may be a valuable nutritional intervention to consider.
18 Oct 2020
Girls with higher body fat percentage and whose parents smoke are likely to undergo precocious puberty, as reported in a study.