Most Read Articles
Elvira Manzano, 28 Jul 2020
The efficacy and cardiovascular (CV) safety of the SGLT2* inhibitor empagliflozin vs DPP-4** inhibitors and GLP-1*** receptor agonists in real-world patients were demonstrated in two interim analyses of the EMPRISE+ study presented at ADA 2020.
Roshini Claire Anthony, 4 days ago

Patients hospitalized with mild-to-moderate COVID-19 who are on angiotensin-converting enzyme (ACE) inhibitors or angiotensin receptor blockers (ARBs) for hypertension should continue these medications, according to primary results of the BRACE CORONA trial presented at ESC 2020.

Tristan Manalac, 09 Jul 2020
Left ventricular assist devices (LVADs) trigger almost immediate favourable metabolic changes in both diabetics and nondiabetics, according to a recent study.
Tristan Manalac, 04 Sep 2020
Anticoagulation therapy may be of value to patients with new-onset atrial fibrillation (AF) associated with sepsis, easing the risk of all-cause mortality and ischaemic stroke without increasing the likelihood of major bleeding, reports a study presented at the Digital 2020 Congress of the European Society of Cardiology (ESC).

ATP-stress CTP an accurate tool for detection of myocardial ischaemia

16 Aug 2020

Adenosine triphosphate (ATP)-stress myocardial computed tomography perfusion (CTP) correlates well with coronary flow velocity reserve (CFVR) for the assessment of myocardial ischaemia, a recent study has shown.

The study included 50 patients (mean age, 69.6±9.4 years; 76 percent male) with stable angina pectoris who underwent both ATP-stress CTP and CFVR imaging. Myocardial ischaemia in CTP was defined qualitatively as perfusion defects, and quantitatively as reductions in myocardial blood flow (MBF). In CFVR, a cut-off value of 2.0 was used during assessment.

Qualitatively, CTP identified myocardial ischaemia in the left anterior descending (LAD) artery region of 25 patients. The mean CFVR score in these regions was 1.9±0.6; in comparison, the average score in those without myocardial ischaemia, as qualitatively defined by CTP, was 2.9±0.8 (p<0.001).

Qualitative CTP was able to predict CFVR <2.0 with an 84.0-percent diagnostic accuracy, along with sensitivity and specificity values of 94.7 percent and 77.4 percent, respectively.

Quantitatively, MBF showed a significant and positive correlation with CFVR (r, 0.630; p<0.0001). Receiver operating characteristic curves identified an optimal MBF cut-off value of 1.43 mL/g/min. At this threshold, the area under the curve was 0.89 and the diagnostic accuracy for detecting CFVR <2.0 was 84.0 percent. The sensitivity and specificity were 94.7 percent and 77.4 percent, respectively

Combining both quantitative and qualitative evaluations, specificity jumped to 96.8 percent, and diagnostic accuracy improved to 94.0 percent.

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Most Read Articles
Elvira Manzano, 28 Jul 2020
The efficacy and cardiovascular (CV) safety of the SGLT2* inhibitor empagliflozin vs DPP-4** inhibitors and GLP-1*** receptor agonists in real-world patients were demonstrated in two interim analyses of the EMPRISE+ study presented at ADA 2020.
Roshini Claire Anthony, 4 days ago

Patients hospitalized with mild-to-moderate COVID-19 who are on angiotensin-converting enzyme (ACE) inhibitors or angiotensin receptor blockers (ARBs) for hypertension should continue these medications, according to primary results of the BRACE CORONA trial presented at ESC 2020.

Tristan Manalac, 09 Jul 2020
Left ventricular assist devices (LVADs) trigger almost immediate favourable metabolic changes in both diabetics and nondiabetics, according to a recent study.
Tristan Manalac, 04 Sep 2020
Anticoagulation therapy may be of value to patients with new-onset atrial fibrillation (AF) associated with sepsis, easing the risk of all-cause mortality and ischaemic stroke without increasing the likelihood of major bleeding, reports a study presented at the Digital 2020 Congress of the European Society of Cardiology (ESC).