Atopic dermatitis tied to active, passive smoking
Active and passive smoking are associated with atopic dermatitis, a new study from Korea reveals.
The cross-sectional study was based on data from the Korea Youth Risk Behaviour Web-based Survey. In the study population of 145,702 adolescents (aged 12 to 18 years), 6.8 percent (n=10,020; mean age 15 years) developed atopic dermatitis 12 months before the survey.
There was a significant difference in active (p=0.003) and passive (p<0.001) smoking between participants who developed atopic dermatitis and those who did not. Significance was established using a Chi-square test with Rao-Scott correction.
After adjusting for potential covariates such as active, passive and e-cigarette smoking, active smoking at a frequency of ≥20 days a month was positively associated with atopic dermatitis (odds ratio [OR], 1.18; 1.07 to 1.29).
Additionally, active smoking had a significant dose-response relationship with the risk of atopic dermatitis (p=0.002).
The same results were obtained for passive smoking, with those who reached frequencies of ≥5 days a week having elevated risks of atopic dermatitis (OR, 1.12; 1.05 to 1.20) and the risk showing a significant dose-response relationship (p<0.001).
In contrast, in the model adjusted for all covariates including active and passive smoking, e-smoking was not significantly associated with the risk of atopic dermatitis (OR, 1.03; 0.95 to 1.12; p=0.436).
“Atopic dermatitis in the past 12 months is significantly associated with active and passive smoking in Korean adolescents. These relationships demonstrated positive associations in accordance with the frequency and dose of active and passive smoking,” the researchers summarized.