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Pearl Toh, Yesterday
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Pearl Toh, 6 days ago
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Atopic dermatitis tied to active, passive smoking

12 Nov 2017

Active and passive smoking are associated with atopic dermatitis, a new study from Korea reveals.

The cross-sectional study was based on data from the Korea Youth Risk Behaviour Web-based Survey. In the study population of 145,702 adolescents (aged 12 to 18 years), 6.8 percent (n=10,020; mean age 15 years) developed atopic dermatitis 12 months before the survey.

There was a significant difference in active (p=0.003) and passive (p<0.001) smoking between participants who developed atopic dermatitis and those who did not. Significance was established using a Chi-square test with Rao-Scott correction.

After adjusting for potential covariates such as active, passive and e-cigarette smoking, active smoking at a frequency of 20 days a month was positively associated with atopic dermatitis (odds ratio [OR], 1.18; 1.07 to 1.29).

Additionally, active smoking had a significant dose-response relationship with the risk of atopic dermatitis (p=0.002).

The same results were obtained for passive smoking, with those who reached frequencies of 5 days a week having elevated risks of atopic dermatitis (OR, 1.12; 1.05 to 1.20) and the risk showing a significant dose-response relationship (p<0.001).

In contrast, in the model adjusted for all covariates including active and passive smoking, e-smoking was not significantly associated with the risk of atopic dermatitis (OR, 1.03; 0.95 to 1.12; p=0.436).

“Atopic dermatitis in the past 12 months is significantly associated with active and passive smoking in Korean adolescents. These relationships demonstrated positive associations in accordance with the frequency and dose of active and passive smoking,” the researchers summarized.

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Most Read Articles
Pearl Toh, Yesterday
First-line therapy with the BTK* inhibitor ibrutinib plus the anti-CD20 immunotherapy rituximab confers significant survival advantage over the current gold-standard regimen of fludarabine, cyclophosphamide, and rituximab (FCR) for young, fit patients with treatment-naïve chronic lymphocytic leukaemia (CLL), according to the E1912 trial, a large cooperative group study supported by the US National Cancer Institute.
6 days ago
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Pearl Toh, 6 days ago
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