Most Read Articles
Dr. Joseph Delano Fule Robles, 6 days ago

A recent study conducted by The University of Hong Kong (HKU) revealed that long-term use of proton pump inhibitors (PPIs) is associated with a significantly increased risk of gastric cancer even in patients who have had Helicobacter pylori eradicated. 

5 days ago
The 5-year survival rates for human papillomavirus (HPV)-associated cancers vary greatly according to age and race, with Caucasians and younger patients tending to have better survival, according to a recent US study.
6 days ago
High levels of marijuana exposure appear to not be longitudinally associated with prevalent albuminuria and substantial changes in estimated glomerular filtration rate by cystatin C (eGFRcys), a recent US epidemiological study has shown.
5 days ago
Men with breast cancer have tumours that are typically of the human epidermal growth factor receptor 2-negative Luminal B subtype and positive for oestrogen receptor, progesterone receptor and androgen receptor, according to the results of the EORTC 10085/TBCRC/BIG/NABCG International Male Breast Cancer Program study.

Asymptomatic reservoirs a potential source of norovirus outbreaks

13 Nov 2017
Qualified stool donors who are being selected can earn up to HKD4,800 per month by participating the donor program as each stool donation will be compensated with HKD200.

Asymptomatic reservoirs appear to be able to transmit large amounts of norovirus (NoV) on their stools, a recent study from Indonesia shows. Thus, this may be a potential source of NoV outbreaks.

Reverse transcription-polymerase chain reaction (PCR) was carried out in 512 stool samples obtained from 18 asymptomatic individuals (aged 20 to 42 years; 66 percent female). NoV viral load was determined using real-time PCR of viral RNA.

Of all stool samples, 14 tested positive for NoV, resulting in an overall detection rate of 2.7 percent. These samples were collected from seven different participants (38.9 percent) who did not significantly differ in sex (p=0.36), use of western toilets (p=0.36) and educational background (p=0.64) from those who did not have NoV-positive stools.

The viral loads were low for most of the positive subjects, with titres ranging from <101 ­to 105 copies/g.

The month with the highest NoV prevalence was determined to be July, followed by April, August and November. The remaining months had relatively low levels of NoV prevalence with the months of June, May and March having no observed infections. The interval of duration between reinfections were 1 to 4 months.

All 14 identified NoV strains from the healthy participants belonged to genogroup II (GII). Majority of the NoV strains (71.4 percent; n=10) were classified as GII.2 while 14.3 percent (n=2) were classified as GII.17. GII.4 Sydney 2012 and GII.1 were each assigned one strain.

“[O]ur findings demonstrated that asymptomatic NoV infections are common in Surabaya, Indonesia, and some of the asymptomatic individuals shed large amounts of viruses similarly to symptomatic cases, suggesting that the excretion of NoV from healthy individuals is one of the sources of NoV outbreaks,” said researchers.

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Most Read Articles
Dr. Joseph Delano Fule Robles, 6 days ago

A recent study conducted by The University of Hong Kong (HKU) revealed that long-term use of proton pump inhibitors (PPIs) is associated with a significantly increased risk of gastric cancer even in patients who have had Helicobacter pylori eradicated. 

5 days ago
The 5-year survival rates for human papillomavirus (HPV)-associated cancers vary greatly according to age and race, with Caucasians and younger patients tending to have better survival, according to a recent US study.
6 days ago
High levels of marijuana exposure appear to not be longitudinally associated with prevalent albuminuria and substantial changes in estimated glomerular filtration rate by cystatin C (eGFRcys), a recent US epidemiological study has shown.
5 days ago
Men with breast cancer have tumours that are typically of the human epidermal growth factor receptor 2-negative Luminal B subtype and positive for oestrogen receptor, progesterone receptor and androgen receptor, according to the results of the EORTC 10085/TBCRC/BIG/NABCG International Male Breast Cancer Program study.