Most Read Articles
18 Apr 2018
Higher intake levels of coffee appear to be associated with reduced risk of developing chronic kidney disease, according to data from the Atherosclerosis Risk in Communities Study.
Jairia Dela Cruz, 5 days ago
Infants delivered via caesarean section may be at increased risk of developing acute lymphoblastic leukaemia, according to a US study. Altered microbiota colonization is a possible explanation for this risk, although clear biological mechanisms have yet to be established.
5 days ago
Treatment with danegaptide does not improve myocardial salvage in patients with ST-segment elevation myocardial infarction (STEMI) undergoing primary percutaneous coronary intervention, according to the results of a phase II study.
4 days ago
Men with high levels of exposure to diesel exhaust are at greater risk of developing amyotrophic lateral sclerosis (AML), as shown in a recent study. This is not true for women.

Asymptomatic reservoirs a potential source of norovirus outbreaks

13 Nov 2017
Qualified stool donors who are being selected can earn up to HKD4,800 per month by participating the donor program as each stool donation will be compensated with HKD200.

Asymptomatic reservoirs appear to be able to transmit large amounts of norovirus (NoV) on their stools, a recent study from Indonesia shows. Thus, this may be a potential source of NoV outbreaks.

Reverse transcription-polymerase chain reaction (PCR) was carried out in 512 stool samples obtained from 18 asymptomatic individuals (aged 20 to 42 years; 66 percent female). NoV viral load was determined using real-time PCR of viral RNA.

Of all stool samples, 14 tested positive for NoV, resulting in an overall detection rate of 2.7 percent. These samples were collected from seven different participants (38.9 percent) who did not significantly differ in sex (p=0.36), use of western toilets (p=0.36) and educational background (p=0.64) from those who did not have NoV-positive stools.

The viral loads were low for most of the positive subjects, with titres ranging from <101 ­to 105 copies/g.

The month with the highest NoV prevalence was determined to be July, followed by April, August and November. The remaining months had relatively low levels of NoV prevalence with the months of June, May and March having no observed infections. The interval of duration between reinfections were 1 to 4 months.

All 14 identified NoV strains from the healthy participants belonged to genogroup II (GII). Majority of the NoV strains (71.4 percent; n=10) were classified as GII.2 while 14.3 percent (n=2) were classified as GII.17. GII.4 Sydney 2012 and GII.1 were each assigned one strain.

“[O]ur findings demonstrated that asymptomatic NoV infections are common in Surabaya, Indonesia, and some of the asymptomatic individuals shed large amounts of viruses similarly to symptomatic cases, suggesting that the excretion of NoV from healthy individuals is one of the sources of NoV outbreaks,” said researchers.

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Most Read Articles
18 Apr 2018
Higher intake levels of coffee appear to be associated with reduced risk of developing chronic kidney disease, according to data from the Atherosclerosis Risk in Communities Study.
Jairia Dela Cruz, 5 days ago
Infants delivered via caesarean section may be at increased risk of developing acute lymphoblastic leukaemia, according to a US study. Altered microbiota colonization is a possible explanation for this risk, although clear biological mechanisms have yet to be established.
5 days ago
Treatment with danegaptide does not improve myocardial salvage in patients with ST-segment elevation myocardial infarction (STEMI) undergoing primary percutaneous coronary intervention, according to the results of a phase II study.
4 days ago
Men with high levels of exposure to diesel exhaust are at greater risk of developing amyotrophic lateral sclerosis (AML), as shown in a recent study. This is not true for women.