Most Read Articles
Pearl Toh, 08 Jun 2016
Middle East Respiratory Syndrome (MERS) patients have more severe illness and a higher mortality rate than non-MERS severe acute respiratory infection (SARI) patients, according to a study presented at the recent American Thoracic Society (ATS) International Conference 2016 held in San Francisco, California, US.
Rachel Soon, 04 Aug 2017

Investment in health crisis response systems during non-pandemic periods is crucial to combating the next inevitable flu pandemic, according to a government representative.

30 Apr 2016
New drug applications approved by US FDA as of 16 - 30 Apr 2016 which includes New Molecular Entities (NMEs) and new biologics. It does not include Tentative Approvals. Supplemental approvals may have occurred since the original approval date.
15 Jan 2017
New drug applications approved by US FDA as of 1 - 15 January 2017 which includes New Molecular Entities (NMEs) and new biologics. It does not include Tentative Approvals. Supplemental approvals may have occurred since the original approval date.

Asthma a risk factor for myelodysplastic syndrome

12 Jan 2017

Asthma may contribute to an added risk of developing myelodysplastic syndrome or chronic myelomonocytic leukaemia (CMML), a recent study suggests.

Researchers looked at a cohort of patients with a first-time hospital-based asthma diagnosis to examine whether asthma was directly related to the development of myelodysplastic syndrome. The total study population comprised 75,995 patients with incident asthma and no history of myelodysplastic syndrome or CMML.

Of the patients, 78 and 9 developed myelodysplastic syndrome and CMML, respectively, during 402,892 person-years.

The cumulative risks of developing myelodysplastic syndrome and CMML were 0.02 percent (95 percent CI, 0.01 to 0.04) and 0.07 percent (0.05 to 0.09) during the first year and the first five years of follow-up, respectively.

Myelodysplastic syndrome and CMML had a standardized incidence ratio of 1.6 (1.3 to 2.0) among asthma patients overall, with little difference across subgroups.

The role of allergies in the development of hematopoietic malignancies is unclear. One potential explanation for this association is the antigen stimulation theory, which suggests that the immune system of allergic individuals is perpetually stimulated by allergens, inducing chronic inflammation, stimulation of cell proliferation and, ultimately, increased risk of malignancy. [Cancer Epidemiol Biomarkers Prev 2014;23:1903–1912]

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Most Read Articles
Pearl Toh, 08 Jun 2016
Middle East Respiratory Syndrome (MERS) patients have more severe illness and a higher mortality rate than non-MERS severe acute respiratory infection (SARI) patients, according to a study presented at the recent American Thoracic Society (ATS) International Conference 2016 held in San Francisco, California, US.
Rachel Soon, 04 Aug 2017

Investment in health crisis response systems during non-pandemic periods is crucial to combating the next inevitable flu pandemic, according to a government representative.

30 Apr 2016
New drug applications approved by US FDA as of 16 - 30 Apr 2016 which includes New Molecular Entities (NMEs) and new biologics. It does not include Tentative Approvals. Supplemental approvals may have occurred since the original approval date.
15 Jan 2017
New drug applications approved by US FDA as of 1 - 15 January 2017 which includes New Molecular Entities (NMEs) and new biologics. It does not include Tentative Approvals. Supplemental approvals may have occurred since the original approval date.