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ARIC: Coffee drinking may lower risk for liver-related hospitalizations

16 Aug 2019

The known benefits of coffee drinking keep on growing as a new study suggests that coffee consumption can lower the risk of liver-related hospitalizations.

This prospective analysis recorded 833 incident cases of liver-related hospitalizations over a median follow-up of 24 years and 152 liver-related deaths over a median follow-up of 25 years. Majority of the participants in the highest category of coffee consumption (≥3 cups/day) were men, white, current smokers and current alcohol drinkers.

In the fully adjusted model, participants drinking at least 3 cups of coffee a day were more likely to have a reduced risk of liver-related hospitalizations as compared with never drinkers (hazard ratio, 0.79, 95 percent CI, 0.63–0.99). After adjusting for covariates, no significant associations were found between coffee consumption and liver-related deaths.

“This [finding] supports current evidence that low and moderate levels of coffee may be protective to the liver,” the authors said.

This study included 14,208 participants aged 45–64 years from the Atherosclerosis Risk in Communities (ARIC) study. Food frequency questionnaires were used to assess coffee consumption based on cups/day at visit 1 (1987–1989) and visit 3 (1993–1995).

Liver-related hospitalizations were defined as a hospitalization with any International Classification of Diseases, Ninth Revision (ICD-9) code related to liver disease identified through cohort surveillance. Liver related-death referred to any death with a liver disease ICD-9 code listed anywhere on the death certificate form.

“Coffee consumption has been found to be associated with reduced risk of chronic conditions such as liver disease,” the authors noted.

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