Most Read Articles
Pearl Toh, 28 Aug 2017
Taking long-chain omega-3 fatty acids (LC-OM3) supplements, mainly EPA* and DHA** omega-3s, was associated with a modest but significant reduction in cardiac death risk, according to a meta-analysis of randomized controlled trials (RCTs).
Rachel Soon, 01 Sep 2018

MIMS Pharmacist presents an overview of a standardized extract of Pinus pinaster bark, and its potential role in slowing down the progression of diabetic retinopathy.

Dr. Lau Hui Ling, 01 Aug 2017
Oral contraceptive selection should be individualized for each patient to yield maximum benefit.
18 Apr 2016
Copper intrauterine device exhibited superior efficacy to injectable progestin contraception in women attending termination of pregnancy services in South Africa, according to a pragmatic, open-label, parallel arm, randomised controlled trial.

Antituberculosis treatment halves risk of uveitis recurrence

25 Apr 2018

In patients with latent tuberculosis (TB)-associated uveitis, treatment with an anti-TB drug cuts the risk of uveitis recurrence by half and delays the onset of first recurrence, as reported in a recent study.

Researchers looked at 199 eyes of 129 patients, of whom 89 patients (69 percent) received anti-TB treatment. Uveitis was managed using local and systemic anti-inflammatory and immunosuppressive therapy.

Data on clinical outcome, vision and treatment were gathered and analysed. Outcomes of interest included best corrected visual acuity (BCVA) and rate of disease recurrence.

Over the follow-up period, mean change in BCVA following treatment was 4.5±1.4 letters. No significant difference was observed between eyes of patients receiving anti-TB treatment and those who did not.

Uveitis recurrence occurred in 68 eyes (34.9 percent; 0.64±0.08 recurrences per year), with eyes of patients receiving anti-TB treatment less likely to develop a recurrence (29.5 percent vs 48.2 percent).

Specifically, anti-TB treatment reduced the odds of developing recurrence by more than half (odds ratio, 0.47; 95 percent CI, 0.29–0.77; p=0.003). Eyes of patients who received the treatment recurred at an estimated median of 120 months vs 51 months in eyes of those who were not treated with an anti-TB drug (p=0.005).

The present data provide positive evidence of the benefit of treating latent TB-related uveitis with an anti-TB drug in addition to appropriate local and systemic anti-inflammatory therapy, researchers said.

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Most Read Articles
Pearl Toh, 28 Aug 2017
Taking long-chain omega-3 fatty acids (LC-OM3) supplements, mainly EPA* and DHA** omega-3s, was associated with a modest but significant reduction in cardiac death risk, according to a meta-analysis of randomized controlled trials (RCTs).
Rachel Soon, 01 Sep 2018

MIMS Pharmacist presents an overview of a standardized extract of Pinus pinaster bark, and its potential role in slowing down the progression of diabetic retinopathy.

Dr. Lau Hui Ling, 01 Aug 2017
Oral contraceptive selection should be individualized for each patient to yield maximum benefit.
18 Apr 2016
Copper intrauterine device exhibited superior efficacy to injectable progestin contraception in women attending termination of pregnancy services in South Africa, according to a pragmatic, open-label, parallel arm, randomised controlled trial.