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Pearl Toh, 6 days ago
Every-two-month injections of the long-acting cabotegravir + rilpivirine were noninferior to once-monthly injections for virologic suppression at 48 weeks in people living with HIV*, according to the ATLAS-2M** study presented at CROI 2020 — thus providing a potential option with more convenient dosing.
Stephen Padilla, 19 Mar 2020
The assumption that children are less vulnerable to the coronavirus disease 2019 (COVID-19) compared to adults is not quite true and may even be dangerous, suggests a recent study.
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Anthropometric indices are accurate predictors of metabolic syndrome in teens

26 Mar 2020
Under new NHS criteria, obese patients “will not get non-urgent surgery until they reduce their weight”.

Anthropometric indices are reliable predictors of metabolic syndrome (MetS), but not of cardiovascular risk markers (CRM), in adolescents, reports a recent Brazil study.

Researchers conducted a cross-sectional analysis of 1,069 adolescents (aged 12–17 years; 570 girls), in whom the following anthropometric indices were measured: body mass index (BMI), waist circumference (WC), waist-to-height ratio (WHR), conicity index (CoI), body shape index (BSI), adolescence-adjusted BSI and body roundness index (BRI).

Receiver operating characteristics (ROC) curves showed that in girls, BMI, WC, WHR and BRI were all decently predictive of elevated blood pressure, with areas under the curve (AUC) values ranging from 0.6 to <0.7. No anthropometric index was predictive of other CRMs, such as triglycerides, fasting glucose, total cholesterol and insulin resistance.

In contrast, all of the indices examined performed excellently for predicting MetS, with AUC values measuring at or above 0.9.

In boys, ROC curves likewise demonstrated that BMI (AUC, 0.739) and WC (AUC, 0.723) had good predictive value for high blood pressure. WHR, BRI and BSI, on the other hand, were less reliable, but still decent (AUC from 0.6 to <0.7). Similar to girls, all anthropometric indices had good to excellent predictive capacity for MetS.

Notably, at the prespecified cutoff values, almost all anthropometric indices showed 100 percent sensitivity for MetS in both girls and boys. The only exception was unadjusted BSI, which had sensitivity values of 80.0 percent and 83.3 percent in girls and boys, respectively.

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Most Read Articles
Pearl Toh, 6 days ago
Every-two-month injections of the long-acting cabotegravir + rilpivirine were noninferior to once-monthly injections for virologic suppression at 48 weeks in people living with HIV*, according to the ATLAS-2M** study presented at CROI 2020 — thus providing a potential option with more convenient dosing.
Stephen Padilla, 19 Mar 2020
The assumption that children are less vulnerable to the coronavirus disease 2019 (COVID-19) compared to adults is not quite true and may even be dangerous, suggests a recent study.
22 Mar 2020
Sustained use of lopinavir-combined regimen appears to confer benefits among patients with the novel coronavirus disease (COVID-19), with improvement possibly indicated by increasing eosinophils, suggests a recent study.
24 Mar 2020
COVID-19 is a novel disease, with no existing immunity. The virus can be transmitted from person to person, quickly and exponentially. Here’s what we can do to slow down the spread, if not contain the outbreak.