Most Read Articles
6 days ago
Higher values of plasma aldosterone concentration (PAC) show a robust association with some metabolic variables, including triglycerides, urinary albumin excretion (UAE), carotid intima-media thickness (cIMT), worse ankle-brachial index (ABI) and major prevalence of carotid plaques, a recent study has shown.
Stephen Padilla, 20 Aug 2019
No association exists between a vegan diet and lower blood pressure (BP) measurements as compared with omnivorous alternatives, a study has found. The effect of a vegan diet in adults is similar to that by portion-controlled diets and those recommended by medical societies.
24 Sep 2019
Obese patients are exposed to greater doses of radiation during radiofrequency ablation for atrial fibrillation, a recent study has found.
01 Oct 2019
Patients with greater ischaemia who underwent positron emission tomography (PET) myocardial perfusion imaging (MPI) have better survival with early revascularization, reports a study. Exploratory analyses reveal a lower threshold than that previously reported for single-photon emission computed tomography (SPECT).

Anaemia predicts cardiovascular, renal events in hypertensives

12 Jun 2019

Anaemia predicts cardiovascular and renal events in hypertensive patients with well-controlled blood pressure, reports a recent study.

Accessing the ATTEMPT-CVD* study, researchers divided 1,213 participants into those who were (n=194; mean age, 70.5±8.5 years; 43 percent male) or were not (n=1,019; mean age, 65.5±9.3 years; 61 percent male) anaemic based on their baseline haemoglobin concentrations. The incidence rates of renal and cardiovascular events were compared between groups, as was blood pressure.

The mean haemoglobin in the anaemic and nonanaemic groups were 11.5±0.8 and 14.4±1.3 g/dL, respectively. Cox proportional hazards analysis showed that the incidence of cardiovascular and renal events was significantly elevated in participants positive for anaemia (hazard ratio [HR], 1.945, 95 percent CI, 1.208–3.130; p=0.0062).

This was specifically true in males (HR, 2.246, 1.213–4.159; p=0.0101), while in females, statistical significance was not achieved (p=0.0749). There was no significant correlation between anaemia and sex (p=0.7875).

Multivariable analysis combined with backward selection further confirmed the significant and independent value of being diagnosed with anaemia for predicting cardiovascular and renal events (adjusted HR, 1.816, 1.116–2.955; p=0.0163).

Other predictors included the male sex (adjusted HR, 1.681, 1.070–2.642; p=0.0242), prior diabetes (adjusted HR, 2.945, 1.688–5.138; p=0.0001) and cardiovascular disease (adjusted HR, 2.445; 1.492–4.007; p=0.0004), and plasma brain natriuretic peptide level ≥19 ng/mL (adjusted HR, 2.049, 1.296–3.240; p=0.0021).

* A trial of telmisartan prevention of cardiovascular disease

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Most Read Articles
6 days ago
Higher values of plasma aldosterone concentration (PAC) show a robust association with some metabolic variables, including triglycerides, urinary albumin excretion (UAE), carotid intima-media thickness (cIMT), worse ankle-brachial index (ABI) and major prevalence of carotid plaques, a recent study has shown.
Stephen Padilla, 20 Aug 2019
No association exists between a vegan diet and lower blood pressure (BP) measurements as compared with omnivorous alternatives, a study has found. The effect of a vegan diet in adults is similar to that by portion-controlled diets and those recommended by medical societies.
24 Sep 2019
Obese patients are exposed to greater doses of radiation during radiofrequency ablation for atrial fibrillation, a recent study has found.
01 Oct 2019
Patients with greater ischaemia who underwent positron emission tomography (PET) myocardial perfusion imaging (MPI) have better survival with early revascularization, reports a study. Exploratory analyses reveal a lower threshold than that previously reported for single-photon emission computed tomography (SPECT).