Most Read Articles
18 May 2020
Immobilization or disuse of the forearm leads to impairment in the ability of a protein-rich meal to promote positive muscle amino acid balance, which is aggravated by dietary lipid oversupply, suggests a study. Disuse also lowers postprandial forearm amino acid uptake, but this is not exacerbated under high-fat conditions.
18 May 2020
Glucagon-like peptide-1 receptor agonists (GLP-1RA) are more effective than basal insulin in the management of total (TC) and low-density lipoprotein cholesterol (LDL-C), reveals a recent study.
17 May 2020
Increased coffee consumption among regular drinkers is associated with higher estimated glomerular filtration rate and confers protection against the risk of chronic kidney disease stages G3–G5 and albuminuria, as shown in a study.
Jairia Dela Cruz, 16 May 2020
Excess weight, greater abdominal fat, inflammation and low physical performance can all contribute to insulin resistance in middle-age Singaporean women, and these variables explain why the condition is more common among women of Chinese than Malay and Indian ethnicities, a study has found.

Alcohol abuse cuts long-term survival from severe acute pancreatitis

05 Aug 2019

While short-term survival is good in young patients with severe acute pancreatitis (SAP), long-term survival is impaired by alcohol abuse, a recent study has shown.

Researchers conducted a retrospective analysis of 435 adults with SAP (median age, 48 years; 81.8 percent male) who underwent intensive care. Majority of the participants (77.0 percent; n=335) suffered from alcoholic SAP, though this was significantly more common among males (82.8 percent vs 48.8 percent; p<0.001).

A total of 357 participants survived to the 90-day follow-up, yielding a short-term survival rate of 82.1 percent. Those who were younger were more likely to survive (median, 47 years vs 61 years; p<0.001). Pancreatitis was the most common underlying cause of death (98.7 percent; n=77).

Stratifying participants according to age groups further highlighted the survival benefit of younger age. The survival rate was 89.5 percent in those <60 years of age and dropped progressively to 60.3 percent and 43.3 percent in patients 60–69 years and 70 years, respectively.

For long-term outcomes, participants were followed for a median of 5.8 years. The resulting 10-year survival estimates were 28.3 percent and 67.9 percent for those older and younger than 60 years, respectively.

Alcohol-related reasons accounted for more than half of the long-term deaths (57.1 percent; n=48). These included any underlying or immediate alcohol-related diseases, alcohol intoxication, and traumatic deaths associated with alcohol use. Acute pancreatitis was the cause of death in 22 (26.2 percent) late mortalities.

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Most Read Articles
18 May 2020
Immobilization or disuse of the forearm leads to impairment in the ability of a protein-rich meal to promote positive muscle amino acid balance, which is aggravated by dietary lipid oversupply, suggests a study. Disuse also lowers postprandial forearm amino acid uptake, but this is not exacerbated under high-fat conditions.
18 May 2020
Glucagon-like peptide-1 receptor agonists (GLP-1RA) are more effective than basal insulin in the management of total (TC) and low-density lipoprotein cholesterol (LDL-C), reveals a recent study.
17 May 2020
Increased coffee consumption among regular drinkers is associated with higher estimated glomerular filtration rate and confers protection against the risk of chronic kidney disease stages G3–G5 and albuminuria, as shown in a study.
Jairia Dela Cruz, 16 May 2020
Excess weight, greater abdominal fat, inflammation and low physical performance can all contribute to insulin resistance in middle-age Singaporean women, and these variables explain why the condition is more common among women of Chinese than Malay and Indian ethnicities, a study has found.