Most Read Articles
Dr Margaret Shi, 18 May 2020

A blood test is shown to be feasible and safe for early detection of multiple cancers in women with no current or known history of cancer, enabling early treatment with curative intent in a subset of individuals.

Christina Lau, 20 Apr 2020

Hippocampal avoidance during whole-brain radiotherapy (HA-WBRT), together with memantine, better preserves cognitive function vs WBRT plus memantine in patients with brain metastases, without compromising survival, a multi-institutional phase III trial has shown.

Natalia Reoutova, 20 May 2020

Cancer patients infected with coronavirus disease 2019 (COVID-19) appear to be at higher risk of severe outcomes, including death, but cancer type and treatment serve as better predictors, according to recent research presented at the American Association for Cancer Research (AACR) 2020 Virtual Annual Meeting I.

At the time of writing, COVID-19 has spread to more than 200 countries and territories, affecting an estimated 4.5 million people and killing over 300,000. Cancer, on the other hand, is newly diagnosed in 18 million people and takes the lives of 10 million every year.

“We have invited physician scientists who are at the epicentre of the COVID-19 pandemic, taking care of patients with cancer. They gathered prospective information to understand the effects of COVID-19 on patients with cancer, are testing new treatments, and are making this knowledge available to the global research community, so we can all benefit from their experience,” said Professor Antoni Ribas from UCLA Medical Center, Los Angeles, California, US, chairperson of the COVID-19 and cancer plenary session of the meeting.

Natalia Reoutova, 28 May 2020

Fasting-mimicking diet (FMD) cycles in combination with endocrine therapy (ET) cause metabolic changes in hormone receptor (HR)-positive breast cancer patients analogous to those observed in animal models, where they are associated with anticancer activity.

Air pollution tied to breast cancer risk

11 Apr 2020

A more polluted air appears to increase the likelihood of developing breast cancer, a recent South Korea study has shown.

Researchers conducted a nationwide, whole-population census study, including the 252 administrative districts of South Korea. Exposure variables were indicators of air pollution, such as nitrogen dioxide (NO2), carbon monoxide (CO), sulfate dioxide (SO2) and 10-µm particulate matter (PM10). At the time of data collection, the South Korean female population was 24,149,865.

Multivariable linear regression modeling, adjusted for altitude, higher education, smoking rate, obesity and gross regional domestic product per capita, showed that air pollutants were directly correlated with breast cancer risk. Every 100-ppb increase in CO, for example, significantly increased the likelihood of the malignancy (odds ratio [OR], 1.08, 95 percent confidence interval [CI], 1.06–1.10).

In absolute terms, this meant that women living in districts with air CO concentrations higher by 100 ppb were 8 percent more likely to develop breast cancer.

NO2 (OR per 10 ppb, 1.14, 95 percent CI, 1.12–1.16), SO2 (OR per 1 ppb, 1.04, 95 percent CI, 1.02–1.05) and PM10 (OR per 10 µg/m3, 1.13, 95 percent CI, 1.09–1.17) also emerged as significant risk factors. Of these, only PM10 independently predicted breast cancer mortality (OR, 1.05, 95 percent CI, 1.01–1.09).

Multi-pollutant models confirmed these findings. All of the four air pollutants examined remained significantly associated with the risk of breast cancer even when additionally adjusted for the other three pollutants.

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Most Read Articles
Dr Margaret Shi, 18 May 2020

A blood test is shown to be feasible and safe for early detection of multiple cancers in women with no current or known history of cancer, enabling early treatment with curative intent in a subset of individuals.

Christina Lau, 20 Apr 2020

Hippocampal avoidance during whole-brain radiotherapy (HA-WBRT), together with memantine, better preserves cognitive function vs WBRT plus memantine in patients with brain metastases, without compromising survival, a multi-institutional phase III trial has shown.

Natalia Reoutova, 20 May 2020

Cancer patients infected with coronavirus disease 2019 (COVID-19) appear to be at higher risk of severe outcomes, including death, but cancer type and treatment serve as better predictors, according to recent research presented at the American Association for Cancer Research (AACR) 2020 Virtual Annual Meeting I.

At the time of writing, COVID-19 has spread to more than 200 countries and territories, affecting an estimated 4.5 million people and killing over 300,000. Cancer, on the other hand, is newly diagnosed in 18 million people and takes the lives of 10 million every year.

“We have invited physician scientists who are at the epicentre of the COVID-19 pandemic, taking care of patients with cancer. They gathered prospective information to understand the effects of COVID-19 on patients with cancer, are testing new treatments, and are making this knowledge available to the global research community, so we can all benefit from their experience,” said Professor Antoni Ribas from UCLA Medical Center, Los Angeles, California, US, chairperson of the COVID-19 and cancer plenary session of the meeting.

Natalia Reoutova, 28 May 2020

Fasting-mimicking diet (FMD) cycles in combination with endocrine therapy (ET) cause metabolic changes in hormone receptor (HR)-positive breast cancer patients analogous to those observed in animal models, where they are associated with anticancer activity.