Most Read Articles
Naomi Rodrig, 15 Jun 2016
An interim analysis from the multinational phase III CASTOR trial, presented recently at the 2016 American Society of Clinical Oncology (ASCO) Annual Meeting, showed that adding daratumumab to the standard two-drug regimen of bortezomib and dexamethasone markedly improved outcomes of patients with recurrent or refractory multiple myeloma.
Roshini Claire Anthony, 22 Feb 2017

Individuals with hepatitis C virus (HCV) infection who achieve a sustained virological response (SVR) have improved liver stiffness and a lower risk of hepatocellular carcinoma (HCC), according to a presentation at the Asian Pacific Association for the Study of the Liver annual meeting (APASL 2017) in Shanghai, China.

24 Feb 2017
Slideshow: Highlights from the 26th Conference of the Asian Pacific Association for the Study of the Liver (APASL), Shanghai, China, February 15 - 19.
Pearl Toh, 09 Mar 2017
Pearl Toh finds out from Professor Anna Lok, director of clinical hepatology at the University of Michigan in Ann Arbor, Michigan, US, on integrating guidelines, research data, and clinical setting in decision making for management of hepatitis B during the recent Asian Pacific Association for the Study of the Liver Annual Meeting held in Shanghai, China.

Aerobic endurance predicts falls-risk exposure more than lower body strength

20 Mar 2017

In female breast cancer patients above the age of 75, exposures to falls-risk depend much more on aerobic endurance than on overall strength of the lower body, a new study shows.

The study included 102 breast cancer patients (mean age 70.2 years) female receiving treatment. For inclusion, patients had to be >65 years of age and have received surgical intervention without reconstructive surgery.

Participants were categorized into three groups according to age: 65 to 69 (n=50), 70 to 74 (n=31) and 75 to 79 (n=21) years. Self-reported falls were determined through a questionnaire. Appropriate tests were used to assess gait and balance disorders, gait speed, dynamic balance, individual agility and gait.

All participants, regardless of group, showed a significant deficit in lower body strength and individual aerobic endurance compared to reference values. Women in the oldest group seemed to have the largest deficit.

In all subgroups, age had a significant effect on gait speed (p<0.05). There was a significant association between risk of falls and gait speed (p<0.05). A higher gait speed reduced this risk.

Furthermore, participants were classified according to their propensity for accidental falls based on the Tinetti POMA test results. In subgroups 2 and 3, where patients are aged >70 years, 13 and 14 percent were classified into the high-risk group, respectively.

Finally, lower body strength was associated with the individual risk of fall in patients below the age of 75 (group 1: p<0.0001; group 2: p=0.0001). On the other hand, aerobic endurance was associated with risk of falls only in patients aged>75 years (p=0.0250).

The findings show that rehabilitation after surgical interventions for cancer is a complex issue.

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Most Read Articles
Naomi Rodrig, 15 Jun 2016
An interim analysis from the multinational phase III CASTOR trial, presented recently at the 2016 American Society of Clinical Oncology (ASCO) Annual Meeting, showed that adding daratumumab to the standard two-drug regimen of bortezomib and dexamethasone markedly improved outcomes of patients with recurrent or refractory multiple myeloma.
Roshini Claire Anthony, 22 Feb 2017

Individuals with hepatitis C virus (HCV) infection who achieve a sustained virological response (SVR) have improved liver stiffness and a lower risk of hepatocellular carcinoma (HCC), according to a presentation at the Asian Pacific Association for the Study of the Liver annual meeting (APASL 2017) in Shanghai, China.

24 Feb 2017
Slideshow: Highlights from the 26th Conference of the Asian Pacific Association for the Study of the Liver (APASL), Shanghai, China, February 15 - 19.
Pearl Toh, 09 Mar 2017
Pearl Toh finds out from Professor Anna Lok, director of clinical hepatology at the University of Michigan in Ann Arbor, Michigan, US, on integrating guidelines, research data, and clinical setting in decision making for management of hepatitis B during the recent Asian Pacific Association for the Study of the Liver Annual Meeting held in Shanghai, China.