Most Read Articles
Harriet Pugsley, MB ChB, MRCOG; Judith Moore, MRCOG, 01 Aug 2013

Most women presenting with complications in early pregnancy are assessed, diagnosed and managed at early pregnancy assessment units (EPAUs). These units aim to provide thorough assessments, access to specialist investigations (scan, human chorionic gonadotrophin [hCG]), a rapid turnaround of results, and co-ordination of further management.

07 Aug 2016
Pravastatin supplementation is associated with improved pregnancy outcomes among women with refractory obstetric antiphospholipid syndrome (APS) who developed preeclampsia (PE) or intrauterine growth restriction (IUGR) during standard antithrombotic therapy, according to a study.
Roshini Claire Anthony, 07 Sep 2016

Estrogen receptor α (ESR1) mutations Y537S and D538G are associated with reduced overall survival (OS) in patients with human epidermal growth factor receptor 2 (HER2)-negative metastatic breast cancer, according to findings of a secondary analysis of the BOLERO-2* clinical trial.

Acupoint stimulation effective for primary dysmenorrhea

07 Oct 2017

Acupoint stimulation effectively relieves pain in primary dysmenorrhea (PD), according to a new meta-analysis.

After applying the selection criteria, 19 randomized controlled studies (RCTs) were found to be eligible for inclusion in the meta-analysis. Studies were retrieved from the databases of PubMed, Embase, the Cochrane Library, CNKI, Wangfang Data and the Chinese Biomedical Literature Database.

Studies that were not RCTs, those that used combination of treatments and those with incomplete data were excluded.

Pooled data from 17 trials showed that acupoint stimulation was significantly more effective than nonsteroidal anti-inflammatory drugs (NSAIDS) in terms of clinical efficacy for patients with PD (odds ratio [OR], 5.57; 95 percent CI, 3.96 to 7.83; p<0.00001).

Similarly, symptom score in PD patients, reported in six trials, was significantly improved by acupoint stimulation (mean difference [MD], 2.99; 2.49 to 3.49; p<0.0001).

Three trials examined pain, as measured by the visual analogue scale. Pooling the findings from these studies, it was found that acupoint stimulation showed no significant benefit than controls in terms of pain improvement (MD, 1.24; -3.37 to 5.85; p=0.60).

In terms of side effects, control treatments had significantly more side effects than acupoint stimulation, according to a pooled analysis of two trials (OR, 0.03; 0.00 to 0.22; p=0.0005).

In assessing methodological quality, researchers used the criteria outlined in Cochrane Handbook for Systematic Reviews. They found that while randomization was correctly followed in most of the studies, only very few reported on allocation concealment, participant blinding and outcome blinding. 

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Most Read Articles
Harriet Pugsley, MB ChB, MRCOG; Judith Moore, MRCOG, 01 Aug 2013

Most women presenting with complications in early pregnancy are assessed, diagnosed and managed at early pregnancy assessment units (EPAUs). These units aim to provide thorough assessments, access to specialist investigations (scan, human chorionic gonadotrophin [hCG]), a rapid turnaround of results, and co-ordination of further management.

07 Aug 2016
Pravastatin supplementation is associated with improved pregnancy outcomes among women with refractory obstetric antiphospholipid syndrome (APS) who developed preeclampsia (PE) or intrauterine growth restriction (IUGR) during standard antithrombotic therapy, according to a study.
Roshini Claire Anthony, 07 Sep 2016

Estrogen receptor α (ESR1) mutations Y537S and D538G are associated with reduced overall survival (OS) in patients with human epidermal growth factor receptor 2 (HER2)-negative metastatic breast cancer, according to findings of a secondary analysis of the BOLERO-2* clinical trial.