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Actinic keratosis risk greater in taller people

31 Jul 2018

There appears to be a significant and positive correlation between height and actinic keratosis (AK), according to a recent South Korea study.

The study included 17,386,083 participants who were divided into five groups according to height. A total of 49,287 AK cases were reported, yielding an incidence rate of 0.314 per 1,000 person-years. AK was most common in participants above the age of 60 years.

Multivariate analysis showed that AK was significantly associated with height. Compared with those in the first quintile, the incidence rate of AK was higher in participants who were in the highest quintile of height (0.32755 vs 0.29771 per 1,000 person-years), as was the likelihood of AK (hazard ratio [HR], 1.284; 95 percent CI, 1.242–1.326).

The risk of AK was likewise significantly higher in participants who were in the second (HR, 1.073; 1.04–1.07), third (HR, 1.193; 1.158–1.23) and fourth (HR, 1.207; 1.169–1.246) quintiles of height. The associations were significant even after adjusting for demographic and socioeconomic factors, alcohol consumption, smoking status, and comorbidities.

In subgroup analyses, the correlation between height and AK risk was more pronounced in males (Q5 vs Q1: HR, 1.375; 1.306–1.447) than in females (Q5 vs Q1: HR, 1.237; 1.184–1.291) and in those at least (Q5 vs Q1: HR, 1.341; 1.285–1.4) vs younger (Q5 vs Q1: HR, 1.222; 1.161–1.286) than 65 years of age.

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Most Read Articles
21 hours ago
Use of potassium citrate and thiazides appears to improve health-related quality of life (HRQOL) among stone formers across all Wisconsin Stone Quality of Life (WISQOL) domains without increasing the likelihood of gastrointestinal complaints and fatigue or sexual complaints, respectively, reports a study.
Pearl Toh, 4 days ago
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2 days ago
Eating high amounts of red and processed meat prior to a diagnosis of colorectal cancer appears to be associated with shorter survival time, although a possible weak association cannot be excluded, a study has shown.
Yesterday
Middle-aged Caucasian men who are dissatisfied with their marriage are at higher risk of sudden cardiac death regardless of other cardiovascular risk factors, a new study reports.