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Absence of dysmenorrhea, cyclic abdominal pain up risk of abdominal wall endometriosis

30 Jul 2017

Cyclic localized abdominal pain, previous laparotomy and absence of dysmenorrhea are significant risk factors for abdominal wall endometriosis, a new study shows.

Compared with 68 controls (mean age 33.5±8.8 years), significantly more women with abdominal wall endometriosis (n=34; mean age 35.2±5.9 years) had abdominal pain (100 vs 26.5 percent; p<0.001) and a history of laparotomy (94.1 vs 14.7 percent; p<0.001).

On the other hand, significantly less women with abdominal wall endometriosis had dysmenorrhea compared with controls (11.8 vs 39.7 percent; p=0.004).

Multivariable analysis showed that cyclic abdominal pain (adjusted odds ratio [OR], 12.46; 95 percent CI, 2.07 to 125.09), absence of dysmenorrhea (adjusted OR, 11.31; 1.51 to 132.56) and previous laparotomy (adjusted OR, 61.9; 12.77 to 533.79) were all associated with abdominal wall endometriosis.

Together, the area under the receiver operating characteristic curve was 0.94 (0.87 to 0.98).

Baseline parity (two vs zero; p<0.001) and body mass index (29.2±6.6 vs 26.4±6.7 kg/m2; p=0.02) were higher, and caesarean delivery (88.2 vs 10.3 percent; p<0.001) and gynaecologic surgeries (zero to 15 vs zero to seven percent; p=0.003) were more common in the abdominal wall endometriosis patients than in controls.

Mean symptom duration was 38.6±31.3 months. None of the patients developed pelvic endometriosis nor had complications after surgery. Repeat surgery was performed on 5.9 percent (n=2) of patients.

Investigators recruited women receiving surgery for endometriosis at the Mayo Clinic between January 1, 2000 and December 31, 2013. The Students t test, Wilcoxon rank sum or Fisher’s exact test were used to compare variables between cases and controls.

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Most Read Articles
6 days ago
Higher activity of plasma xanthine oxidase appears to be linked to insulin resistance and liver dysfunction among type 2 diabetes mellitus (T2DM) patients with metabolic syndrome (MetS), according to a recent Japan study.
6 days ago
Use of quetiapine among critically ill patients rarely leads to corrected QT (QTc) interval prolongation, reports a new study.
15 Jun 2018
New drug applications approved by US FDA as of 1 - 15 June 2018 which includes New Molecular Entities (NMEs) and new biologics. It does not include Tentative Approvals. Supplemental approvals may have occurred since the original approval date.
Pearl Toh, 6 days ago
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