Most Read Articles
01 Nov 2019
Discontinuation of antitumour necrosis factor (anti-TNF) therapy for perianal Crohn’s disease is highly likely to lead to relapse, with some patients even requiring defunctioning surgery, according to a study conducted across Asia.
Pearl Toh, 22 Oct 2019
Among patients with a large perforated peptic ulcer (PPU), undergoing omental patch repair confers comparable perioperative outcomes as gastrectomy, a retrospective local study shows.
Roshini Claire Anthony, 07 May 2019

The trend in liver disease-related mortality in individuals with HIV has changed, with a reduction in the incidence of viral hepatitis-related deaths and an increase in non-alcoholic fatty liver disease (NAFLD)-related deaths, according to a study presented at the International Liver Congress (ILC 2019).

Prof. Khean-Lee Goh, Yong Yeh Lee, 15 Oct 2019

The global community is celebrating World Stomach Day on October 2, now in its second year, and the date itself reminds us of the very first report of Helicobacter pylori in 1982.

Abdominal obesity strongly predictive of advanced colorectal neoplasia in men

17 Jul 2019

Abdominal obesity, measured by waist circumference (WC), is a more robust predictor of the risk of advanced colorectal neoplasia (CRN) than overall obesity, measured by body mass index (BMI), in men, according to a study.

The authors performed a cross-sectional study on 154,552 asymptomatic examinees (mean age, 42.6 years; 65.2 percent men) who underwent colonoscopy for a health check-up to assess whether WC was associated with CRN risk, independent of BMI.

In patients in WC quartiles 1, 2, 3 and 4, the prevalence rate of CRN was 15.6 percent, 18.1 percent, 20.4 percent and 22.0 percent among men, respectively. The corresponding CRN rate among women was 7.8 percent, 9.4 percent, 12.2 percent and 15.8 percent.

WC and BMI were independently associated with overall CRN and nonadvanced CRN in both men and women. The association of BMI with advanced CRN decreased to null in men after adjusting for WC (Q2: odds ratio [OR], 0.93, 95 percent CI, 0.79–1.10; Q3: OR, 0.85, 0.71–1.03; Q4: OR, 0.99, 0.80–1.22, compared with Q1; p-trend=0.822).

On the other hand, the association of WC with advanced CRN was consistent even after adjusting for BMI (Q2: OR, 1.20, 1.02–1.42; Q3: OR, 1.45, 1.20–1.75; Q4: OR, 1.64, 1.32–2.04, compared with Q1; p-trend<0.001).

Neither WC nor BMI correlated with advanced CRN risk in women.

“Our findings suggest that abdominal obesity is more strongly predictive of advanced CRN than overall obesity in men,” the authors said, noting that previous studies have shown an association between abdominal obesity and CRN.

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Most Read Articles
01 Nov 2019
Discontinuation of antitumour necrosis factor (anti-TNF) therapy for perianal Crohn’s disease is highly likely to lead to relapse, with some patients even requiring defunctioning surgery, according to a study conducted across Asia.
Pearl Toh, 22 Oct 2019
Among patients with a large perforated peptic ulcer (PPU), undergoing omental patch repair confers comparable perioperative outcomes as gastrectomy, a retrospective local study shows.
Roshini Claire Anthony, 07 May 2019

The trend in liver disease-related mortality in individuals with HIV has changed, with a reduction in the incidence of viral hepatitis-related deaths and an increase in non-alcoholic fatty liver disease (NAFLD)-related deaths, according to a study presented at the International Liver Congress (ILC 2019).

Prof. Khean-Lee Goh, Yong Yeh Lee, 15 Oct 2019

The global community is celebrating World Stomach Day on October 2, now in its second year, and the date itself reminds us of the very first report of Helicobacter pylori in 1982.