Most Read Articles
Roshini Claire Anthony, 04 Apr 2019

In addition to an intensive weight loss programme, the use of continuous positive airway pressure (CPAP) could improve absolute weight loss in individuals with obesity and obstructive sleep apnoea (OSA), according to a study presented at ENDO 2019.

2 days ago
The ketogenic and Modified Atkin’s diets are effective treatments for children with refractory epilepsy of genetic aetiology, a new study suggests.
12 Apr 2019
Long-acting beta2-agonist (LABA) plus long-acting muscarinic antagonist (LAMA) combinations compare with inhalers containing both LABA and corticosteroid (LABA-ICS) in terms of reducing chronic obstructive pulmonary disease (COPD) exacerbations, although the LAMA-LABA combination is more favourable as it is associated with fewer episodes of severe pneumonia, according to a study.
3 days ago
Extremely premature neonates who have been exposed to pre-eclampsia in utero are at high risk of developing severe respiratory distress syndrome and severe bronchopulmonary dysplasia, according to a study.

A healthy lifestyle cuts colorectal cancer risk

17 Dec 2018

Modifiable lifestyle behaviours, such as diet and exercise, significantly affect the risk of colorectal cancer (CRC), a recent study has shown.

The study included 4,092 CRC patients (mean age 68.2±10.8 years; 60.8 percent male) and 3,032 healthy controls (mean age 68.2±10.4 years; 60.9 percent male), in whom a healthy lifestyle score was derived from five lifestyle behaviours: smoking, alcohol consumption, body fat, physical activity and diet. A genetic risk score based on 53 known variants was also included in the analysis.

Multivariable logistic regression analysis showed that each individual modifiable factor was associated with a reduced risk of CRC: nonsmoking (odds ratio [OR], 0.82; 95 percent CI, 0.72–0.94), alcohol intake within the recommended levels (OR, 0.83; 0.74–0.94), a healthy diet (OR, 0.70; 0.63–0.78), physical activity meeting the recommended levels (OR, 0.88; 0.76–1.03) and a healthy body mass index (BMI; OR, 0.71; 0.63–0.79).

Moreover, those who meet two, three, four or five healthy lifestyle behaviours were significantly less likely to develop colorectal (p<0.0001), colon (p<0.0001) and rectal (p<0.0001) cancer than those who had none or one healthy lifestyle factor.

Similarly, each additional healthy lifestyle factor resulted in a significant drop in the risk of colorectal (OR, 0.77; 0.73–0.81), colon (OR, 0.77; 0.73–0.81) and rectal (OR, 0.77; 0.72–0.82) cancer.

In terms of population attributable fractions, 45 percent of all CRC cases could be accounted for by nonadherence to all five modifiable healthy lifestyle behaviours.

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Most Read Articles
Roshini Claire Anthony, 04 Apr 2019

In addition to an intensive weight loss programme, the use of continuous positive airway pressure (CPAP) could improve absolute weight loss in individuals with obesity and obstructive sleep apnoea (OSA), according to a study presented at ENDO 2019.

2 days ago
The ketogenic and Modified Atkin’s diets are effective treatments for children with refractory epilepsy of genetic aetiology, a new study suggests.
12 Apr 2019
Long-acting beta2-agonist (LABA) plus long-acting muscarinic antagonist (LAMA) combinations compare with inhalers containing both LABA and corticosteroid (LABA-ICS) in terms of reducing chronic obstructive pulmonary disease (COPD) exacerbations, although the LAMA-LABA combination is more favourable as it is associated with fewer episodes of severe pneumonia, according to a study.
3 days ago
Extremely premature neonates who have been exposed to pre-eclampsia in utero are at high risk of developing severe respiratory distress syndrome and severe bronchopulmonary dysplasia, according to a study.