• Strong COX-2 Inhibition1
• High Tissue Penetration2
• High Efficacy & Once Daily Dosing2,3
• Proven Safety For Long Term Use4

References:
1. Sugimoto et al, Drug Dev Res. 2016;77:206-11
2. Yataba et al, Eur J Clin Pharmacol (2016) 72:53-59
3. LOCOA® Approved Package Insert
4. Yataba et al, Clin Drug Investig. 2016;36:673-682.