Most Read Articles
Rachel Soon, 26 Jun 2018

MIMS Pharmacist presents an overview of phosphatidylcholine's physiological role, as well as contemporary research on its pharmacology and effects.

17 Mar 2018
Nonvitamin K antagonist oral anticoagulants (NOAC)-associated intracerebral haemorrhage (ICH) and vitamin K antagonists-ICH appear to have similar ICH volume, haematoma expansion, functional outcome and mortality, results of a recent meta-analysis have shown.
Rachel Soon, 07 Jun 2018

For the first time, healthcare professionals may now refer to the Malaysian Clinical Practice Guidelines on the Management of Diabetes in Pregnancy for treatment options.

Dr Renly Lim, 01 Aug 2018
Palliative care uses an integrated, multidisciplinary approach to reduce suffering and to improve the quality of life of patients battling with life-threatening illnesses.

3 barriers associated with apt use of oral chemotherapies

14 Mar 2018

A recent survey has revealed three factors preventing the appropriate use of oral chemotherapies, and they are as follows: misunderstanding about the timing of drug with food, stopping drug without informing physicians and difficulty understanding labelling directions.

A total of 93 patients (51 percent female) taking oral chemotherapies with chronic myeloid leukaemia, renal cell carcinoma, breast cancer and colorectal cancer completed the survey. The participants were well-educated, with 69 percent (n=62) having completed some college, and mostly older than 50 years of age (n=54).

Of the patients, 30 percent reported forgetting to take their medication at least “sometimes.” Higher rates of forgetfulness in taking their oral chemotherapy were seen among younger patients (<50 vs ≥50 years; p=0.002), those with shorter treatment duration (<6 vs ≥6 months; p=0.03) or with chronic myeloid leukaemia (vs other diagnoses; p=0.015).

Twenty-one patients (23 percent) said they intentionally skipped their oral chemotherapies. Of these participants, eight (38 percent) failed to inform their physicians. There were 28 patients (41 percent) taking oral chemotherapy with significant food–drug effects who did not consider their last meal before taking their medication, and 55 (80 percent) had no understanding of such potential interactions.

In addition, 36 patients (39 percent) did not look at labelling directions, while 14 (15 percent) had a difficult time understanding such labels.

“A multipronged approach is needed to optimize communication of directions for optimal oral chemotherapy use,” the authors said, adding that appropriate use of oral chemotherapy is a challenge for both patients and clinicians.

A 30-question survey was created to determine the frequency and reasons for reducing or skipping doses, sources of information for oral chemotherapy use, perceived importance of food–drug effects, and ease of understanding labelling directions.

Digital Edition
Asia's trusted medical magazine for healthcare professionals. Get your MIMS Pharmacist - Malaysia digital copy today!
Sign In To Download
Editor's Recommendations
Most Read Articles
Rachel Soon, 26 Jun 2018

MIMS Pharmacist presents an overview of phosphatidylcholine's physiological role, as well as contemporary research on its pharmacology and effects.

17 Mar 2018
Nonvitamin K antagonist oral anticoagulants (NOAC)-associated intracerebral haemorrhage (ICH) and vitamin K antagonists-ICH appear to have similar ICH volume, haematoma expansion, functional outcome and mortality, results of a recent meta-analysis have shown.
Rachel Soon, 07 Jun 2018

For the first time, healthcare professionals may now refer to the Malaysian Clinical Practice Guidelines on the Management of Diabetes in Pregnancy for treatment options.

Dr Renly Lim, 01 Aug 2018
Palliative care uses an integrated, multidisciplinary approach to reduce suffering and to improve the quality of life of patients battling with life-threatening illnesses.