systemic%20lupus%20erythematosus
SYSTEMIC LUPUS ERYTHEMATOSUS
Systemic lupus erythematosus is a chronic, multisystem, inflammatory, autoimmune disorder characterized by formation of autoantibodies directed against self-antigens and immune-complex formation.
It can be suspected when ≥2 organ systems are involved.
It is predominantly diagnosed in females of childbearing age, rarely diagnosed before 8 years old.
Clinical presentation varies in different patients and the disease activity varies over time in a single patient. Majority of patients have arthralgia of the hand.

Patient Education

  • Patients should be provided w/ information, counseling & support
  • Involve all the family members in counseling regarding the disease
    • Family must have a thorough understanding of the disease, its potential severity & complications of the disease & treatment
  • Patient must learn to cope & monitor the disease when he or she is at the right age
    • He or she should be able to distinguish signs & symptoms that may precede a disease flare & consult w/ the physician immediately
    • Educate all patients regarding possible complications from unplanned pregnancy, poor compliance,recreational drug use & infection
    • For married patients, contraception is important during the active phase of the disease
  • Advise patients to join other systemic lupus erythematosus (SLE) patients in support groups
  • Patients must be advised to wear clothing w/ long sleeves, use umbrella or sunscreen lotion & refrain from sunbathing to prevent exacerbation of dermatologic symptoms
    • Use sunscreen w/ at least a sun-protection factor (SPF) of 15
  • Patients must have appropriate diet to prevent obesity, osteoporosis & dyslipidemia
    Advise patients to seek medical help when they have fever
    • Exposure to immunosuppressive drugs used in SLE may predispose patients to infection
  • Patients on corticosteroids should have a no added
    • Regular exercise to maintain appropriate weight & bone density
    • Advise patients that fatigue & stress are associated w/ disease flares
  • Immunization should be updated for all patients
    • Patients should have appropriate immunizations (ie influenza, pneumococcal, HPV)
    • Patients w/ SLE are often complement deficient & are at risk for encapsulated organisms
  • Antibiotic prophylaxis for all dental, genitourinary & other invasive procedures for patients at high risk of infections (eg patients w/ valvular abnormalities, on immunosuppressive therapy)
  • Patients should routinely undergo gynecologic assessments, dental care & ophthalmologic exam especially for patients taking corticosteroids
  • Psychological support may also be necessary
Digital Edition
Asia's trusted medical magazine for healthcare professionals. Get your MIMS Rheumatology digital copy today!
DOWNLOAD
Editor's Recommendations
Most Read Articles
Elvira Manzano, 6 days ago
Bisphosphonates have proven antifracture efficacy and remain to be the cornerstone of osteoporosis treatment. However, a drug holiday is of particular importance with bisphosphonates due to some signals with long-term use of the drug, including rare incidence of atypical femoral fracture (AFF) and osteonecrosis of the jaw (ONJ), says a leading endocrinologist at AFOS 2017.
Yesterday
Drinking coffee, whether caffeinated or decaffeinated, is associated with a reduced risk of cardiovascular disease (CVD) and ischaemic heart disease (IHD) mortality in patients with a prior myocardial infarction (MI), according to a recent study.
3 days ago
Breast cancer patients have notably different microbiomes in the local breast tissue and urinary tract, a recent study reveals. Particularly, species in the Methylobacterium genus are reduced in the local breast tissue while the urinary tract is enriched in gram-positive bacteria.
Pearl Toh, 13 Oct 2017
Women with higher plasma tryptophan concentrations were less likely to have poor sleep quality during pregnancy, especially among those with anxiety symptoms, according to the GUSTO* study.