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SYSTEMIC LUPUS ERYTHEMATOSUS
Systemic lupus erythematosus is a chronic, multisystem, inflammatory, autoimmune disorder characterized by formation of autoantibodies directed against self-antigens and immune-complex formation.
It can be diagnosed with a single organ involvement such as lupus nephritis.
It is predominantly diagnosed in females of childbearing age.
Clinical presentation varies in different patients and the disease activity varies over time in a single patient. Majority of patients have arthralgia of the hand.

Differential Diagnosis

  • Antiphospholipid antibody syndrome
  • Drug-induced lupus
  • Early rheumatoid arthritis
  • Fibromyalgia with positive ANA
  • Idiopathic thrombocytopenic purpura
  • Other vasculitides
  • Scleroderma
  • Sjogren’s syndrome
  • Systemic sclerosis
  • Undifferentiated connective tissue disease
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