systemic%20lupus%20erythematosus%20(pediatric)
SYSTEMIC LUPUS ERYTHEMATOSUS (PEDIATRIC)
Systemic lupus erythematosus (SLE) is a chronic, multisystem, inflammatory, autoimmune disorder characterized by formation of autoantibodies directed against self-antigens and immune-complex formation.
Clinical presentation varies in different patients and the disease activity varies over time in a single patient. Childhood-onset SLE has a greater disease severity and earlier disease damage than in adults with SLE.

Systemic%20lupus%20erythematosus%20(pediatric) Patient Education

Patient/Parent Education

  • Patients should be provided with information, counseling and support
  • Involve all the family members in counseling regarding the disease
    • Family must have a thorough understanding of the disease, its potential severity and complications of the disease and treatment
  • Patient must learn to cope and monitor the disease when he or she is at the right age
    • He or she should be able to distinguish signs and symptoms that may precede a disease flare and consult with the physician immediately
    • Educate all patients regarding possible complications from unplanned pregnancy, poor compliance, recreational drug use and infection
  • Advise patients to join other SLE patients in support groups
  • Patients must be advised to refrain from sunbathing, wear clothing with long sleeves and use umbrella or sunscreen lotion to prevent exacerbation of dermatologic symptoms
    • Use sunscreen with at least a sun-protection factor (SPF) of 15-30 to prevent dermal or systemic disease flares upon exposure to ultraviolet light 
  • Patients must have appropriate diet to prevent obesity, osteoporosis and dyslipidemia
  • Patients on corticosteroids should have a no-added-salt, low-fat and calcium-sufficient diet  
    • Supplementation with calcium and vitamin D is recommended
  • Advise patients to seek medical help when they have fever
    • Exposure to immunosuppressive drugs used in SLE may predispose patients to infection
  • Encourage patients to maintain a normal lifestyle
    • Regular exercise to maintain appropriate weight and bone density
    • Advise patients that fatigue and stress are associated with disease flares
    • Smoking cessation is recommended
  • Immunization should be updated for all patients
    • Patients should have appropriate immunizations (ie influenza, pneumococcal)
    • Patients with SLE are often complement deficient and are at risk for encapsulated organisms
  • Antibiotic prophylaxis for all dental, genitourinary and other invasive procedures for patients at high risk of infections (eg patients with valvular abnormalities, on immunosuppressive therapy) 
  • Patients should routinely undergo gynecologic assessments, dental care and ophthalmologic exam especially for patients taking corticosteroids and Hydroxychloroquine
  • Psychological support may also be necessary
Digital Edition
Asia's trusted medical magazine for healthcare professionals. Get your MIMS JPOG - Malaysia digital copy today!
Sign In To Download
Editor's Recommendations
Most Read Articles
01 Dec 2020
Tetanus toxoid 5 Lf, diphtheria toxoid 2 Lf, pertussis toxoid 2.5 mcg, filamentous haemagglutinin 5 mcg, fimbriae types 2 and 3 5 mcg, pertactin 3 mcg
Dr. Hsu Li Yang, Dr. Tan Thuan Tong, Dr. Andrea Kwa, 08 Jan 2021
Antimicrobial resistance has become increasingly dire as the rapid emergence of drug resistance, especially gram-negative pathogens, has outpaced the development of new antibiotics. At a recent virtual symposium, Dr Hsu Li Yang, Vice Dean (Global Health) and Programme Leader (Infectious Diseases), NUS Saw Swee Hock School of Public Health, presented epidemiological data on multidrug-resistant (MDR) gram-negative bacteria (GNB) in Asia, while Dr Tan Thuan Tong, Head and Senior Consultant, Department of Infectious Diseases, Singapore General Hospital (SGH), focused on the role of ceftazidime-avibactam in MDR GNB infections. Dr Andrea Kwa, Assistant Director of Research, Department of Pharmacy, SGH, joined the panel in an interactive fireside chat, to discuss challenges, practical considerations, and solutions in MDR gram-negative infections. This Pfizer-sponsored symposium was chaired by Dr Ng Shin Yi, Head and Senior Consultant of Surgical Intensive Care, SGH.
Pearl Toh, 26 Nov 2020
Inhaled corticosteroid (ICS) should be the mainstay of long-term asthma management — such is the key message of the latest Singapore ACE* Clinical Guidance (ACG) for asthma, released in October 2020.
Audrey Abella, 5 days ago
A pilot telemedicine initiative may be an alternative for facilitating delivery of intravenous iron (IVI) for individuals requiring iron supplementation.