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SYSTEMIC LUPUS ERYTHEMATOSUS (PEDIATRIC)
Systemic lupus erythematosus (SLE) is a chronic, multisystem, inflammatory, autoimmune disorder characterized by formation of autoantibodies directed against self-antigens and immune-complex formation.
Clinical presentation varies in different patients and the disease activity varies over time in a single patient. Childhood-onset SLE has a greater disease severity and earlier disease damage than in adults with SLE.

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TAF during pregnancy curbs HBV transmission from mother to child
Pearl Toh, 21 Nov 2020
Antiviral treatment with tenofovir alafenamide fumarate (TAF) during pregnancy in highly viraemic mothers effectively prevents mother-to-child transmission (MTCT) of hepatitis B virus (HBV) with no safety concerns, according to two studies presented during the AASLD 2020 Liver Meeting.
Multifaceted intervention reduces liquid medication dosing errors in kids
11 Dec 2020
A multifaceted intervention that consists of a simplified dosing handout, a teaching session, teach-back, and provision of a standardized dosing device facilitates safe dosing of liquid acetaminophen and ibuprofen by parents or guardians of children discharged from the emergency department, according to a study.
Amoxicillin-clavulanate regimen for PBB: 4 weeks no better than 2 weeks
Roshini Claire Anthony, 28 Sep 2020

A 4-week course of amoxicillin-clavulanate in children with protracted bacterial bronchitis (PBB) does not improve cough resolution rates compared with a 2-week course, according to a study from Australia. However, the longer course may significantly extend time to first cough exacerbation.