Systemic lupus erythematosus is a chronic, multisystem, inflammatory,
autoimmune disorder characterized by formation of autoantibodies
directed against self-antigens and immune-complex formation.
It can be suspected when ≥2 organ systems are involved.
It is predominantly diagnosed in females of childbearing age, rarely diagnosed before 8 years old.
Clinical presentation varies in different patients and the disease
activity varies over time in a single patient. Majority of patients have
arthralgia of the hand.
Parenteral antibiotic therapy duration for bacteraemic urinary tract infection (UTI) in young infants may be safely shortened, according to a recent study showing that recurrence and readmission or emergency department revisitation rates are comparable between a ≤7-day and a longer therapy course.