Systemic lupus erythematosus is a chronic, multisystem, inflammatory,
autoimmune disorder characterized by formation of autoantibodies
directed against self-antigens and immune-complex formation.
It can be suspected when ≥2 organ systems are involved.
It is predominantly diagnosed in females of childbearing age, rarely diagnosed before 8 years old.
Clinical presentation varies in different patients and the disease
activity varies over time in a single patient. Majority of patients have
arthralgia of the hand.
Maternal influenza and Tdap (tetanus toxoid, reduced diphtheria toxoid, acellular pertussis) vaccinations during pregnancy do not increase the risk for hospitalization or death in infants, a study has shown.
Adults who develop peanut allergy in adulthood are less likely to receive a physician diagnosis of their allergy or use epinephrine compared with those with childhood-onset peanut allergy, according to a study from the US.