Syphilis%20-%20primary Patient Education

Patient Education

Patient needs to be informed about the nature of the infection, importance of taking the full course of medication,and possible side effects especially in pregnant patients in whom fetal distress or preterm labor may ensue
Counsel patients on possible complications of sexually transmitted infection (STI)

Advise patients on how to lower their risk of acquiring sexually transmitted infections (STIs)

Tailor counseling to the patient’s specific risk factors
Abstinence, condom use
Careful selection of sex partners

Reactions to Treatment

Jarisch-Herxheimer reaction
- An acute febrile reaction associated with headache, myalgia, or chills that occurs within 2 hours after any treatment for syphilis, especially with penicillin, which resolves within 24 hours
- Can be prevented by giving Prednisolone for 3 days and starting the anti-treponemal treatment 24 hours after Prednisolone was started
Procaine reaction (Procaine psychosis or mania)
- Secondary to inadvertent intravenous (IV) injection of Procaine penicillin that lasts for 20 minutes
- May cause hallucinations, convulsions or fear of imminent death
- May be decreased by “aspiration technique of injection”; may give Diazepam if seizure occurs
Anaphylactic shock
- Penicillin is one of the most common causes of anaphylaxis and should be managed with Epinephrine

The role of oral antivirals in COVID-19 treatment: Who, when, and how?

Dr. Roger Paredes, Dr. Nicola Petrosillo, Dr. Petrick Periyasamy, 30 Jan 2023

Though most countries have eased pandemic restrictions, there is no room for complacency in managing COVID-19, which continues to cause significant morbidity and mortality.

At a recent symposium, esteemed experts Dr Roger Paredes, Head of Department of Infectious Diseases at the Hospital Universitari Germans Trias i Pujol, Badalona, Catalonia, Spain, and Dr Nicola Petrosillo, Head of the Infection Prevention and Control and Infectious Disease Service at University Hospital Campus Bio-Medico, Rome, Italy, gave global perspectives on the continuing unmet needs in the COVID-19 outpatient landscape and discussed the role of antiviral treatment options in patients at risk of progressing to severe COVID-19. Dr Petrick Periyasamy, Head of Infectious Diseases Unit, Medical Department, UKM Medical Centre, Kuala Lumpur, Malaysia, chaired the session.

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Tackling multidrug-resistant gram-negative bacterial infections in critically ill patients: Challenging the standard approach

Dr. Asok Kurup, Dr. Kenneth Chan, 07 Dec 2020

The rising incidence of infections caused by multidrug-resistant (MDR) gram-negative bacteria has become a serious health threat and a major challenge for intensivists. Against a backdrop of high patient mortality and risk factors for infection in intensive care units (ICU), early adequate therapy is of paramount importance. At a recent Pfizer-sponsored symposium, Dr Asok Kurup, Infectious Disease Physician, Singapore presented the implications of MDR gram-negative infections in critically ill patients in Asia, while Dr Kenneth Chan, Respiratory Physician and Intensivist, Singapore highlighted the role of ceftazidime-avibactam (Zavicefta) and shared published real-world data on ceftazidime-avibactam.