scleroderma
SCLERODERMA
Scleroderma is a connective tissue disorder characterized by skin thickening and fibrosis. It is rare, autoimmune and chronic.
It has an idiopathic cause and not contagious.
Early microvascular damage, mononuclear cell infiltrates and slowly developing fibrosis are the important features of the tissue lesions.
The leading causes of death are pulmonary fibrosis and pulmonary arterial hypertension.

Scleroderma Patient Education

Patient Education

  • An exercise program designed by a physiotherapist is most crucial
    • To reduce contractures and functional impairment
    • To minimize joint deformities
    • To keep the blood freely flowing
  • Rest if joints become inflamed
  • Skin care is very important to keep a good supply of blood flowing to the skin
    • Keep the whole body warm to help open the blood vessels of the skin, especially in the hands and feet
    • Avoid strong detergents or other substances that can irritate the skin
    • Prevent drying of skin
    • Use moisturizers to soften and protect the skin
  • Cosmetic makeup may be used to cover up lesions
    • Inactive lesions with atrophic changes may be managed with injectable cosmetic fillers, injection of autologous fat transplantation or surgical excision
  • Avoid high doses of vitamin C (>1000 mg) as it promotes collagen formation
  • Avoid emotional stress as it reduces blood flow
  • Quit smoking
  • Minimize caffeine intake
  • Avoid sympathomimetic decongestant medications (eg Pseudoephedrine)
  • Avoid high-dose corticosteroid use (>15 mg of Prednisone daily) if possible
  • Check blood pressure regularly to monitor for possible complications
Editor's Recommendations
Most Read Articles
Pearl Toh, 2 days ago
The combination therapy comprising carfilzomib, cyclophosphamide and dexamethasone (KCd) is effective, with a tolerable safety profile, in an Asian cohort with high-risk multiple myeloma (MM) — thus providing a more economical alternative as a potential upfront regimen in resource-limited settings, according to leading experts during a myeloma education webinar.
Audrey Abella, 4 days ago
Extremes of sleep duration (≤5 or ≥10 hours/day), which is a known mortality risk factor in the general population, may increase absolute mortality in adults with type 2 diabetes (T2D), a prospective study has shown.
Pearl Toh, 21 Sep 2020
Early and sustained treatments with simplified regimen are the key to achieving good asthma control, said experts during a presentation at the ERS 2020 Congress.
Roshini Claire Anthony, 12 Oct 2020

Insulin icodec, an in-development basal insulin analogue administered once weekly, was as effective as once-daily insulin glargine in patients with type 2 diabetes (T2D) insufficiently controlled with metformin with or without a DPP-4* inhibitor, according to a phase II trial presented at EASD 2020.