Scleroderma is a connective tissue disorder characterized by skin thickening and fibrosis. It is rare, autoimmune and chronic.
It has an idiopathic cause and not contagious.
Early microvascular damage, mononuclear cell infiltrates and slowly developing fibrosis are the important features of the tissue lesions.
The leading causes of death are pulmonary fibrosis and pulmonary arterial hypertension.

Follow Up

  • Patients w/ localized scleroderma w/ deep tissue lesions should have an annual monitoring even after treatment cessation as the disease may relapse
  • Prognosis is better w/ localized scleroderma than systemic scleroderma
  • Re-evaluation of symptomatic treatment every 4-6 mths should be done to prevent complications or further deterioration
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