scleroderma
SCLERODERMA
Scleroderma is a connective tissue disorder characterized by skin thickening and fibrosis. It is rare, autoimmune and chronic.
It has an idiopathic cause and not contagious.
Early microvascular damage, mononuclear cell infiltrates and slowly developing fibrosis are the important features of the tissue lesions.
The leading causes of death are pulmonary fibrosis and pulmonary arterial hypertension.
Drug Information
Editor's Recommendations
Most Read Articles
28 May 2019
Trifarotene is safe, well-tolerated and effective in treating both facial and truncal acne, according to two phase III trials.
08 May 2019
Antinuclear antibody (ANA) negativity appears to increase the likelihood of developing malignancy in patients with adult-onset dermatomyositis (DM) within 3 years of diagnosis of their DM, according to a recent study.
20 May 2019
Three treatments of ablative fractional CO2 laser (AFCO2L) yield improvements in burn scar pain, itch and dermal architecture 6 weeks after treatment, a recent study has found.
11 Apr 2019
Immune checkpoint inhibitor therapy may lead to various inflammatory reactions with differing degrees of severity, suggests a recent study. Most rashes respond to topical treatment, but immunotherapy is often interrupted by immunobullous and exfoliative presentations.