scleroderma
SCLERODERMA
Scleroderma is a connective tissue disorder characterized by skin thickening and fibrosis. It is rare, autoimmune and chronic.
It has an idiopathic cause and not contagious.
Early microvascular damage, mononuclear cell infiltrates and slowly developing fibrosis are the important features of the tissue lesions.
The leading causes of death are pulmonary fibrosis and pulmonary arterial hypertension.
Drug Information

Indication: Pulmonary arterial HTN (PAH) in patients of WHO functional class II-IV.

Indication: Acute & chronic rheumatic fever, RA, bronchial asthma, myositis, dermatitis.

Bufencon
betamethasone dipropionate + betamethasone disodiu...

Indication: Rheumatic disorders, collagen disease, allergic states.

Diprospan
betamethasone dipropionate + betamethasone disodiu...

Indication: Adjunctive treatment of acute & chronic corticosteroid-responsive disorders.

Indication: Chronic stable angina pectoris; HTN.

1  /  3
Editor's Recommendations
Most Read Articles
21 Apr 2020
A bidirectional association exists between alopecia areata (AA) and major depressive disorder (MDD) among probands and unaffected siblings, reveals a study. This suggests that shared familial mechanisms tend to cause AA and MDD.
16 Feb 2020
A 1.5% ruxolitinib cream does not seem to be effective for patients with alopecia areata, a recent phase II study has found.
17 May 2020
Treatment with serlopitant helps lessen pruritus associated with mild-to-moderate psoriasis, results of a phase II trial have shown. This supports the continued development of serlopitant for this condition.
Roshini Claire Anthony, 18 May 2020

Post hoc analyses of the LIBERTY AD SOLO 1 & 2* and ADOL** trials demonstrated significant reductions in pruritus, anxiety, and depression with dupilumab in adults and adolescents with moderate-to-severe atopic dermatitis (AD).