Scabies is a contagious disease caused by the mite Sarcoptes scabiei var hominis.
The affected individual usually complains of having a highly pruritic rash that occurs at night.
It occurs more often in children <15 years of age, sexually active young adults, the immunocompromised and in persons living in crowded living conditions (eg nursing homes, military barracks).
Transmission is typically by direct skin contact with an infected person and in adults, sexual transmission is common.
Diagnosis is made based on clinical presentation and can be confirmed by microscopic identification of mites, eggs or mite feces
Scabies should be suspected in a patient who presents with a highly pruritic rash with nocturnal predominance
Scabies is highly suggested if there is also a history of contact with an infected person or if there is a history of contact with family member or sexual partner who has pruritic lesions with nocturnal predominance
Scabies is caused by the mite: Sarcoptes scabiei var hominis
Occurs more often in children <15 years, sexually active young adults, the immunocompromised and in persons living in crowded living conditions (eg nursing homes, military barracks)
Transmission is typically by direct skin contact with an infected person and in adults, sexual transmission is common
Though there is limited documentation, transmission by fomites may be possible (especially in cases of crusted scabies where a large amount of parasites are involved)
The mites can live for up to 30 days on a host and remain alive for 3 days on furniture, bedding, etc
Signs and Symptoms
Primary symptom is generalized pruritus, which is usually worse at night
Pruritus is caused by a delayed (type IV) hypersensitivity reaction to the mite and its products (saliva, eggs and feces) once the host becomes sensitized
Hypersensitivity occurs 3-6 weeks after infestation but occurs in 1-3 days with re-infestation because the host has been previously sensitized
Dr. Hsu Li Yang, Dr. Tan Thuan Tong, Dr. Andrea Kwa,
08 Jan 2021
Antimicrobial resistance has become increasingly dire as the rapid emergence of drug resistance, especially gram-negative pathogens, has outpaced the development of new antibiotics. At a recent virtual symposium, Dr Hsu Li Yang, Vice Dean (Global Health) and Programme Leader (Infectious Diseases), NUS Saw Swee Hock School of Public Health, presented epidemiological data on multidrug-resistant (MDR) gram-negative bacteria (GNB) in Asia, while Dr Tan Thuan Tong, Head and Senior Consultant, Department of Infectious Diseases, Singapore General Hospital (SGH), focused on the role of ceftazidime-avibactam in MDR GNB infections. Dr Andrea Kwa, Assistant Director of Research, Department of Pharmacy, SGH, joined the panel in an interactive fireside chat, to discuss challenges, practical considerations, and solutions in MDR gram-negative infections. This Pfizer-sponsored symposium was chaired by Dr Ng Shin Yi, Head and Senior Consultant of Surgical Intensive Care, SGH.