sarcoidosis%20-%20pulmonary
SARCOIDOSIS - PULMONARY
Sarcoidosis is a multisystem disease which may present with non-specific symptoms or symptoms related to organ-specific involvement.
Non-specific symptoms include fever, malaise, fatigue and weight loss.
Pulmonary involvement is seen in >90% of sarcoidosis patients.

Introduction

  • A multisystem disease which may present w/ non-specific symptoms or symptoms related to organ-specific involvement

Signs and Symptoms

Non-specific Symptoms

  • Fever
  • Malaise, fatigue
  • Weight loss

Pulmonary Involvement

  • Pulmonary involvement is seen in >90% of sarcoidosis patients
  • Symptoms include:
    • Cough
    • Dyspnea
    • Chest pain or discomfort
  • Sarcoidosis commonly presents as an interstitial disease
  • One half of cases are detected incidentally by chest X-ray abnormality in asymptomatic patients
  • Initial pulmonary defects may either be restrictive or obstructive
  • Symptoms of sarcoidosis are usually already present for a month prior to diagnosis

Findings on Routine Chest X-Ray

  • 30-50% of patients are asymptomatic & are diagnosed by chest X-rays obtained for non-pulmonary indications
  • X-rays may show hilar adenopathy, infiltrates, or fibrosis

Related to Involvement of Other Organs

  • Palpable lymph nodes
  • Cardiac arrhythmias
  • Erythema nodosum, lupus pernio or other dermatologic manifestations
  • Uveitis
  • Cranial nerve palsies
  • Joint pains
  • Hypercalcemia & hypercalciuria
Digital Edition
Asia's trusted medical magazine for healthcare professionals. Get your MIMS Respirology - Malaysia digital copy today!
Sign In To Download
Editor's Recommendations
Most Read Articles
16 Jan 2017
There are various ear, nose, and throat (ENT) conditions which present to the GP’s clinic. Dr Jason Hwang, an ENT Consultant from the Department of Otolaryngology at Gleneagles Hospital in Singapore, speaks on how the majority of the conditions can be effectively managed at the primary care level seeing that these can be treated medically without the need for surgical intervention.
16 Dec 2016
Two of the most common hospital-acquired, ventilator-associated nonfermentative gram-negative pneumonia pathogens—Acinetobacter baumannii and Pseudomonas aeruginosa—develop significant resistance to most therapeutic options available, and they should be managed with combination therapies until new antimicrobial agents are developed, according to a study.
24 May 2018
In children and adolescents with cystic fibrosis (CF), synbiotic supplementation appears to be effective at reducing proinflammatory markers such as interleukin (IL)-6 and -8, and nitric oxide metabolites (NOx), a recent study has found.
15 Apr 2018
The use of transbronchial lung biopsy (TBLB) appears to be safe and effective for the pathological diagnosis of lymphangioleiomyomatosis (LAM), suggests a recent study.