sarcoidosis%20-%20pulmonary
SARCOIDOSIS - PULMONARY
Sarcoidosis is a multisystem disease which may present with non-specific symptoms or symptoms related to organ-specific involvement.
Non-specific symptoms include fever, malaise, fatigue and weight loss.
Pulmonary involvement is seen in >90% of sarcoidosis patients.

Introduction

  • A multisystem disease which may present w/ non-specific symptoms or symptoms related to organ-specific involvement

Signs and Symptoms

Non-specific Symptoms

  • Fever
  • Malaise, fatigue
  • Weight loss

Pulmonary Involvement

  • Pulmonary involvement is seen in >90% of sarcoidosis patients
  • Symptoms include:
    • Cough
    • Dyspnea
    • Chest pain or discomfort
  • Sarcoidosis commonly presents as an interstitial disease
  • One half of cases are detected incidentally by chest X-ray abnormality in asymptomatic patients
  • Initial pulmonary defects may either be restrictive or obstructive
  • Symptoms of sarcoidosis are usually already present for a month prior to diagnosis

Findings on Routine Chest X-Ray

  • 30-50% of patients are asymptomatic & are diagnosed by chest X-rays obtained for non-pulmonary indications
  • X-rays may show hilar adenopathy, infiltrates, or fibrosis

Related to Involvement of Other Organs

  • Palpable lymph nodes
  • Cardiac arrhythmias
  • Erythema nodosum, lupus pernio or other dermatologic manifestations
  • Uveitis
  • Cranial nerve palsies
  • Joint pains
  • Hypercalcemia & hypercalciuria
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