sarcoidosis%20-%20pulmonary
SARCOIDOSIS - PULMONARY
Sarcoidosis is a multisystem disease which may present with non-specific symptoms or symptoms related to organ-specific involvement.
Non-specific symptoms include fever, malaise, fatigue and weight loss.
Pulmonary involvement is seen in >90% of sarcoidosis patients.

Introduction

  • A multisystem disease which may present w/ non-specific symptoms or symptoms related to organ-specific involvement

Signs and Symptoms

Non-specific Symptoms

  • Fever
  • Malaise, fatigue
  • Weight loss

Pulmonary Involvement

  • Pulmonary involvement is seen in >90% of sarcoidosis patients
  • Symptoms include:
    • Cough
    • Dyspnea
    • Chest pain or discomfort
  • Sarcoidosis commonly presents as an interstitial disease
  • One half of cases are detected incidentally by chest X-ray abnormality in asymptomatic patients
  • Initial pulmonary defects may either be restrictive or obstructive
  • Symptoms of sarcoidosis are usually already present for a month prior to diagnosis

Findings on Routine Chest X-Ray

  • 30-50% of patients are asymptomatic & are diagnosed by chest X-rays obtained for non-pulmonary indications
  • X-rays may show hilar adenopathy, infiltrates, or fibrosis

Related to Involvement of Other Organs

  • Palpable lymph nodes
  • Cardiac arrhythmias
  • Erythema nodosum, lupus pernio or other dermatologic manifestations
  • Uveitis
  • Cranial nerve palsies
  • Joint pains
  • Hypercalcemia & hypercalciuria
Digital Edition
Asia's trusted medical magazine for healthcare professionals. Get your MIMS Respirology - Malaysia digital copy today!
Sign In To Download
Editor's Recommendations
Most Read Articles
Pearl Toh, 24 Nov 2016
New treatments such as pirfenidone and nintedanib slow lung function decline and progression of idiopathic pulmonary fibrosis (IPF), although response to treatment can vary dramatically among patients, according to a presentation at the 21st Congress of the Asian Pacific Society of Respirology (APSR 2016) held in Bangkok, Thailand.
16 Oct 2016
Irritable bowel syndrome and asthma share a bidirectional association, a new study reports. Further, atopy potentially plays a role in the underlying mechanisms of this association.
Audrey Abella, 09 May 2018
The potent and highly selective RET* inhibitor BLU-667 was well-tolerated and exhibited promising clinical activity among patients with advanced, RET-altered solid cancers that progressed despite multikinase inhibitor therapy, according to data presented at AACR 2018.