rhinosinusitis%20-%20acute,%20bacterial%20(pediatric)
RHINOSINUSITIS - ACUTE, BACTERIAL (PEDIATRIC)
Treatment Guideline Chart
Rhinosinusitis is the mucosal inflammation of the nose and paranasal sinuses caused by bacteria lasting >10 days for up to 4 weeks, symptoms resolve completely and may either be persistent or severe.
It is often preceded by a viral upper respiratory tract infection.
Signs & symptoms are nonspecific and it is typically difficult to differentiate from viral upper respiratory tract infection.
Streptococcus pneumoniae is the most common cause followed by nontypeable Haemophilus influenzae.

Rhinosinusitis - Acute, Bacterial (Pediatric) References

  1. Bousquet J, Khaltaev N, Cruz AA, et al; World Health Organization; GA(2)LEN; Allergen. Allergic Rhinitis and its Impact on Asthma (ARIA) 2008 update (in collaboration with the World Health Organization, GA(2)LEN and AllerGen). Allergy. 2008 Apr;63(Suppl 86):008-160. http://www.ncbi.nlm.nih.gov/pubmed/?term=18331513. PMID: 18331513
  2. Wallace DV, Dykewicz MS, Bernstein DI, et al. The diagnosis and management of rhinitis: an updated practice parameter. J Allergy Clin Immunol. 2008 Aug;122(Suppl 2):S1-S84. doi: 10.1016/j.jaci.2008.06.003. PMID: 18662584
  3. American Academy of Pediatrics. Subcommittee on Management of Sinusitis and Committee on Quality Improvement. Clinical practice guideline: management of sinusitis. Pediatrics. 2001 Sep;108(3):798-808. http://pediatrics.aappublications.org/. PMID: 11533355
  4. Anon JB, Jacobs MR, Poole MD, et al; Sinus and Allergy Health Partnership. Antimicrobial treatment guidelines for acute bacterial rhinosinusitis. Otolaryngol Head Neck Surg. 2004 Jan;130(1)(Suppl):001-45. PMID: 14726904
  5. Chow AW, Benninger MS, Brook I, et al. IDSA clinical practice guideline for acute bacterial rhinosinusitis in children and adults. Clin Infect Dis. 2012 Apr;54(8):e72-e112. doi: 10.1093/cid/cir1043. Accessed 09 Oct 2013. PMID: 22438350
  6. Fokkens WJ, Lund VJ, Mullol J, et al; European Position Paper on Nasal Polyps group. European position paper on rhinosinusitis and nasal polyps 2007. Rhinol Suppl. 2007;20:1-136. PMID: 17844873
  7. Garbutt JM, Goldstein M, Gellman E, et al. A randomized, placebo-controlled trial of antimicrobial treatment for children with clinically diagnosed acute sinusitis. Pediatrics. 2001 Apr;107(4):619-625. PMID: 11335733
  8. Green RJ. Symptomatic treatment of upper respiratory tract symptoms in children. S Afr Fam Pract. 2006;48(4):38-42
  9. Meltzer EO, Hamilos DL, Hadley JA, et al. Rhinosinusitis: establishing definitions for clinical research and patient care. J Allergy Clin Immunol. 2004 Dec;114(Suppl 6):S155-S212. PMID: 15577865
  10. Morris P, Leach A. WITHDRAWN: Antibiotics for persistent nasal discharge (rhinosinusitis) in children. Cochrane Database of Systematic Reviews. 2007 Jul(3). doi: 10.1002/14651858.CD001094.pub2. PMID: 17636651
  11. Pichichero ME. A review of evidence supporting the American Academy of Pediatrics recommendation for prescribing cephalosporin antibiotics for Penicillin-allergic patients. Pediatrics. 2005 Apr;115(4):1048-1057. PMID: 15805383
  12. Piccirillo JF, Mager DE, Frisse ME, et al. Impact of first-line vs second-line antibiotics for the treatment of acute uncomplicated sinusitis. J Am Med Assoc. 2001 Oct;286(15):1849-1856. PMID: 11597286
  13. Small CB, Bachert C, Lund VJ, et al. Judicious antibiotic use and intranasal corticosteroids in acute rhinosinusitis. Am J Med. 2007 Apr;120(4):289-294. PMID: 17398218
  14. Zacharisen M, Casper R. Pediatric sinusitis. Immunol Allergy Clin North Am. 2005 May;25(2):313-332. PMID: 15878458
  15. Gilbert DN, Moellering RC, Eliopoulos GM, et al. The Sanford guide to antimicrobial therapy. 40th. Sperryville, VA: Antimicrobial Therapy Inc; 2010.
  16. Rhinosinusitis. In: Hay WW, Levin MJ, Sondheimer JM, et al. Current Diagnosis and Treatment in Pediatrics. 18th. New York: McGraw-Hill; 2007.
  17. Pappas DE, Hendley JD. Sinusitis. In: Behrman RE, Kliegman RM, Jenson HB, eds. Nelson Textbook of Pediatrics. 18th. Philadelphia: Saunders, Elsevier; 2007.
  18. Brook I, Gooch WM III, Jenkins SG, et al. Medical management of acute bacterial sinusitis. Recommendations of a Clinical Advisory Committee on Pediatric and Adult Sinusitis. St. Louis, MO: Annals Publishing Company; 2000:20
  19. MedWormhttp://www.medworm.com/rss/index.php/Allergy-%26-Immunology/3/http://www.medworm.com/rss/medicalfeeds/specialities/Allergy-Immunology.xml
  20. MedWormhttp://www.medworm.com/rss/index.php/Pediatrics/33/http://www.medworm.com/rss/medicalfeeds/specialities/Pediatrics.xml
  21. MedWormhttp://www.medworm.com/rss/index.php/Respiratory-Medicine/40/http://www.medworm.com/rss/medicalfeeds/specialities/Respiratory-Medicine.xml
  22. Institute for Clinical Systems Improvement (ICSI). Health care guideline: diagnosis and treatment of respiratory illness in children and adults. ICSI. http://www.icsi.org. 2007.
  23. Acute Bacterial Sinusitis Guideline Team, Cincinnati Children’s Hospital Medical Center. Evidence-based care guideline for medical management of acute bacterial sinusitis in children 1 through 17 years of age. Guideline 16. Cincinnati, OH: Cincinnati Children’s Hospital Medical Center. http://www. antibioticos.msc.es/. Jul 2006.
  24. Alberta Medical Association. The diagnosis and management of acute bacterial sinusitis. Alberta Medical Association. http://www.albertadoctors.org. 2006.
  25. Lynch JS. What are the new guidelines for the management of bacterial rhinosinusitis. Medscape. http://www.medscape.com/.
  26. American College of Physicians. The Physicians’ Information and Education Resource. Acute sinusitis. American College of Physicians. http://pier.acponline.org. 2007.
  27. Wald ER, Applegate KE, Bordley C, et al. Clinical practice guideline for the diagnosis and management of acute bacterial sinusitis in children aged 1 to 18 years. Pediatrics. 2013 Jul;132(1):e262-e280. doi: 10.1542/peds.2013-1071. PMID: 23796742
  28. Ip S, Fu L, Balk E, et al. (Tufts-New England Medical Center EPC, Boston,Mass). Update on acute bacterial rhinosinusitis. Evidence report/technology assessment No. 124. AHRQ Publication No.:05-E020-2. Contract No.:290-02-0022. Chap 3058. Agency for Healthcare Research and Quality. http://www.ncbi.nlm. nih.gov/books/bv.fcgi?rid= hstat1b. June 2005.
  29. Centers for Disease Control and Prevention. Pediatric treatment recommendations. CDC. https://www.cdc.gov/. Feb 2017.
  30. Wald ER. Acute bacterial rhinosinusitis in children: clinical features and diagnosis. UpToDate. https://www.uptodate.com/. Apr 2021. Accessed 23 Jan 2018.
  31. Wald ER. Acute bacterial rhinosinusitis in children: microbiology and treatment. UpToDate. https://www.uptodate.com/. Apr 2020. Accessed 23 Jan 2018.
  32. Esposito S, Bianchini S, Bosis S, et al. . A randomized, placebo-controlled, double-blinded, single-centre, phase IV trial to assess the efficacy and safety of OM-85 in children suffering from recurrent respiratory tract infections. J Transl Med. 2019 Aug;17(1):284. doi:10.1186/s12967-019-2040-y. PMID: 31443716
  33. Fokkens WJ, Lund VJ, Hopkins C, et al. European position paper on rhinosinusitis and nasal polyps 2020. Rhinology. 2020 Feb;58(Suppl S29):1-464. doi:10.4193/Rhin20.600. PMID: 32077450
  34. Schaad UB. OM-85 BV, an immunostimulant in pediatric recurrent respiratory tract infections: a systematic review. World J Pediatr. 2010 Feb;6(1):5-12. doi:10.1007/s12519-010-0001-x. PMID: 20143206
  35. Orlandi RR, Kingdom TT, Smith TL, et al. International consensus statement on allergy and rhinology: rhinosinusitis 2021. Int Forum Allergy Rhinol. 2021 Mar;11(3):213-739. doi: 10.1002/alr.22741. PMID: 33236525
  36. Peters AT, Patel G. Rhinosinusitis: Synopsis. . World Allergy Organization. https://www.worldallergy.org/. Jan 2021.
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