Rhinosinusitis is the mucosal inflammation of the nose and paranasal sinuses caused by bacteria lasting >10 days for up to 4 weeks, symptoms resolve completely and may either be persistent or severe.
It is often preceded by a viral upper respiratory tract infection.
Signs & symptoms are nonspecific and it is typically difficult to differentiate from viral upper respiratory tract infection. Streptococcus pneumoniae is the most common cause followed by nontypeable Haemophilus influenzae.
Children who undergo adenoidectomy, tonsillectomy, or both (adenotonsillectomy) within the first 9 years of life may have an elevated long-term risk of respiratory, allergic, or infectious diseases, results from a Denmark-based study show.
Not only are broad-spectrum antibiotics no better than narrow-spectrum antibiotics in reducing treatment failures and improving other patient-centred outcomes, their use may come with more side effects than narrow-spectrum antibiotics in children with acute respiratory tract infections (ARTIs), suggests a recent study.
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A 2-week course of the immunotherapy drug teplizumab delayed the onset of type 1 diabetes (T1D) in individuals at high risk for the condition, according to a phase II trial conducted by the TrialNet Study Group and presented at ADA 2019.