Rhinosinusitis is the mucosal inflammation of the nose and paranasal sinuses caused by bacteria lasting >10 days for up to 4 weeks, symptoms resolve completely and may either be persistent or severe.
It is often preceded by a viral upper respiratory tract infection.
Signs & symptoms are nonspecific and it is typically difficult to differentiate from viral upper respiratory tract infection. Streptococcus pneumoniae is the most common cause followed by nontypeable Haemophilus influenzae.
Levels of serum proteins, particularly the leucine-rich alpha-2-glycoprotein 1 (LRG1), can be used as biomarkers for the diagnosis of Kawasaki disease (KD) and accurate identification of its phases, a new proteomic study reveals.