Following etanercept (ETN) withdrawal, a relapse occurs in a significant proportion of patients with juvenile idiopathic arthritis (JIA) who maintain clinically inactive disease (CID) for at least 6 months, a recent study has found.
The use of the bisphosphonate risedronate led to a significant reduction in periprosthetic bone mineral density (BMD) loss around an uncemented femoral stem for up to 6 months following total hip arthroplasty (THA), a meta-analysis has shown.
Tocilizumab monotherapy or combined with conventional synthetic (cs)disease-modifying antirheumatic drugs (DMARDs) represents a valuable option in the treatment of rheumatoid arthritis (RA) patients with inadequate response to biologic (b)DMARDS, according to a recent study.
A robust association exists between crystal-proven gout and increased prevalence of cardiovascular disease (CVD), a recent study has found. Additionally, characteristic gout severity factors correlate with CVD in patients with gout.
There is high long-term retention of the first tumour necrosis factor inhibitor (TNFi) administered to patients with spondyloarthritis (SpA), particularly for males with axial disease, reports a study. Major response within the first year of treatment is the strongest predictor of long-term TNFi survival.
Discontinuation of tocilizumab in rheumatoid arthritis (RA) patients who have achieved remission is feasible with continued methotrexate (MTX) therapy, according to 2-year data from the SURPRISE study. Moreover, retreatment with tocilizumab is effective for suppressing flares with or without MTX.
More than half of the increase in cardiovascular disease (CVD) risk associated with osteoarthritis can be attributed to the use of nonsteroidal anti-inflammatory drugs (NSAIDs), suggests a study presented at the EULAR 2018 Congress.
A dual-hormone artificial pancreas (DAP) with a rapid delivery of insulin and pramlintide in a fixed ratio improves glycaemic control and reduces glucose variability in adults with type 1 diabetes (T1D) compared with first-generation artificial pancreas delivering insulin alone, according to a study presented at ADA 2018.
More intensive lowering of LDL-C levels was associated with a progressively greater survival benefit than less intensive approach, when the baseline LDL-C levels were ≥100 mg/dL, reveals a meta-analysis of 34 randomized trials.