Dr. Priscilla Wong, Dr. Lydia Tam, Prof. LS Tam, 20171110000000
This case report highlights that psoriatic arthritis is a heterogenous disease affecting multiple disease domains, and effective treatment requires thorough assessment of each of these different domains.
Spinal fractures are often the result of underlying osteoporosis. Radha Chitale spoke with Dr. Hee Hwan Tak, medical director and senior consultant at the Pinnacle Spine & Scoliosis Centre at Mount Elizabeth Medical Centre, about managing osteoporotic spinal fractures in primary care.
Fractures are a common result of trauma. Associated osteoporosis and overuse injuries can also result in fractures. The fracture pattern depends on the magnitude of the force, duration and direction, and the rate at which it acts. A fracture occurs when the stress applied exceeds the plastic strain of the bone and goes beyond its yield point.
Osteoarthritis (OA) is a degenerative form of arthritis and is the most common type of arthritis today. It involves all the weight-bearing joints of the body, as well as often-used joints like the hands and the spine. OA of the spine is generally referred to as spondylosis.
Ofatumumab appears to be effective and well-tolerated in the treatment of patients with long-standing systemic lupus erythematosus, offering an alternative to the B cell–depleting agent rituximab, according to a study.
Compared to other tumour necrosis factor–α inhibitors (TNFi), infliximab remains superior in reducing Bath Ankylosing Spondylitis Disease Activity Index (BASDAI) at 12 weeks, results of a network meta-analysis (NMA) have shown. However, it was sensitive to inclusion of an open-label trial, and its efficacy faded at 24 weeks.