Patients with ankylosing spondylitis (AS) are nearly twice as likely to harm themselves compared with the general population, a Canadian study has shown, highlighting the need for tailored preventive strategies in these patients.
Roshini Claire Anthony speaks with Dr Annie Law, a consultant at the Department of Rheumatology & Immunology, Singapore General Hospital, on how primary care physicians can help in the management of systemic lupus erythematosus (SLE).
Rheumatoid arthritis patients who use low-dose aspirin in primary prevention of cardiovascular (CV) disease have similar risks of major toxicity and CV events as those who are not exposed to aspirin, according to a secondary analysis of the PRECISION* trial.
In gluteal tendinopathy, corticosteroid injection (CSI) use and education plus exercise (EDX) both lead to higher rates of patient-reported global improvement and lower pain intensity in the short term compared with a wait-and-see (WS) approach, according to a recent study, adding that EDX is better than CSI use.
The use of the tumour necrosis factor (TNF) inhibitor etanercept was associated with structure-modifying effects (ie, reduction in erosion and increase in backfill) as reflected by MRI scans of the sacroiliac joints (SIJ) of patients with nonradiographic axial spondyloarthritis (nr-axSpA), according to a post hoc analysis of the EMBARK* trial.
A 36-year-old banker with good past health presented to our rheumatology clinic with a 6-month history of bilateral wrist pain. He initially sought medical attention in the private sector for a 2-month history of bilateral symmetrical wrist pain and swelling.
Patients with type 2 diabetes (T2D) experienced reductions in plasma uric acid concentrations and subsequently, fewer gout events following treatment with fenofibrate, according to a post hoc analysis of the FIELD* trial.
The addition of the oral Janus kinase inhibitor tofacitinib to csDMARDs* resulted in improvements in patient-reported outcomes (PROs) such as physical function, health-related quality of life (HRQoL), and pain in patients with rheumatoid arthritis (RA), according to a sub-study of the ORAL Sync** trial.
The use of subcutaneous golimumab, a fully human anti-TNFα* monoclonal antibody, resulted in significant improvement in clinical responses in children with active polyarticular course of juvenile idiopathic arthritis (polyJIA), according to the GO KIDS** trial.
Interleukin (IL)-18 inhibition using the recombinant human IL-18 binding protein tadekinig alfa demonstrated early signs of efficacy and a favourable safety profile in patients with adult-onset Still’s disease (AOSD), a rare inflammatory disease of unknown aetiology, a phase II study shows.
Patients who received a combination of ticagrelor plus aspirin within 24 hours of undergoing coronary artery bypass grafting (CABG) had significantly improved saphenous vein graft patency rates 1 year post-procedure compared with those who only received aspirin, according to findings of the DACAB* trial.
Higher activity of plasma xanthine oxidase appears to be linked to insulin resistance and liver dysfunction among type 2 diabetes mellitus (T2DM) patients with metabolic syndrome (MetS), according to a recent Japan study.