Antibiotic-refractory Lyme arthritis (ARLA) and treatment-associated toxicity occur more frequently among older children and those with prolonged arthritis, arthritis limited to the knees or poor initial response to antibiotics, according to a study.
Serum chitotriosidase levels appear to be useful in predicting a poor prognosis in patients with antimelanoma differentiation-associated gene 5 antibody (anti-MDA5)–positive dermatomyositis (DM)/clinically amyopathic DM-associated interstitial lung disease (DM/CADM-ILD), suggests a study.
Ultrasound may provide valuable information for the differential diagnosis of acute erosive arthritis, with a recent study showing that subcutaneous tissue changes and periosteal vascularity are more common in acute osteomyelitis (OM), whereas periosteal tophaceous material distinguishes gouty arthritis from acute OM and rheumatoid arthritis.
Concomitant use of conventional synthetic disease-modifying antirheumatic drug (csDMARD) results in a significantly lower risk for discontinuation of biologic (b)DMARD because of adverse events (AEs) among patients with rheumatoid arthritis (RA), according to a recent study.
Intra-articular glucocorticoid (IAGC) injection is associated with rapid clinical resolution and reduced need for additional treatment, making it an effective and safe second-line strategy for persistent Lyme arthritis in children, a recent study has shown.
Men who undergo flexible cystoscopy, particularly with a longer dwell time, may benefit from intraurethral lidocaine as it provides significant pain reduction, suggest the results of a meta-analysis. Evidence is lacking for other tested interventions.