Some psoriatic arthritis (PsA) patients still experience substantial pain and fatigue despite treatment, a study has shown. These persisting conditions negatively affect health-related quality of life (HRQoL), physical function, and work productivity.
Patients with Takayasu arteritis (TA) are at greater risk of experiencing severe ischaemic events (SIEs), which occur early in the disease, according to a study, adding that aggressive treatment can lead to a favourable prognosis in this population.
An exercise programme lasting for 3 months has been shown to confer positive long-term effects on leisure time physical activity in individuals with axial spondyloarthritis (axSpA), indicating a more favourable health profile, according to a study.
In the treatment of patients with gout and hyperuricemia, use of febuxostat does not appear to come with an increased hazard of mortality or adverse cardiovascular (CV) outcomes, according to the results of a meta-analysis.
Patients with Crohn’s disease risk developing osteoporosis and related fractures, but this may be countered by performing combined impact and resistance training exercises, which confer benefits for bone mineral density and muscle function, a study has shown.
Diabetes is a key risk factor for heart failure (HF), which is the leading cause of hospitalization in patients with or without diabetes. SGLT-2* inhibitors (SGLT-2is) have been shown to reduce the risk of hospitalization for HF (HHF) regardless of the presence or absence of diabetes.
The substitution of isoleucine to leucine at amino acid 97 (I97L) in the core region of the hepatitis B virus (HBV) seems to reduce its potency, decreasing the efficiency of both infection and the synthesis of the virus’ covalently closed circular (ccc) DNA, reports a new study presented at The Liver Meeting Digital Experience by the American Association for the Study of Liver Diseases (AASLD 2020).