Treatment with rituximab (RTX) results in better 2-year progression-free survival (PFS) compared to cyclophosphamide (CYC) despite similar PFS at 6 months in patients with antisynthetase syndrome (AS)-related interstitial lung disease (ILD), a study has shown.
In patients with early rheumatoid arthritis (RA), vitamin D deficiency is associated with more active and severe disease at baseline and is a predictor of disability and radiographic progression, suggests a study.
Treatment with E6011, a novel cell trafficking inhibitor targeting the fractalkine (FKN)‐CX3CR1 interaction, confers modest benefits in rheumatoid arthritis (RA), according to the results of a phase II trial.
Repeated doses of diclofenac etalhyaluronate (DF-HA) yield improvements in knee osteoarthritis (OA) pain without major safety signals, with the effect occurring as early as week 1, according to the results of a phase II trial.
Patients with psoriatic arthritis (PsA) may show residual disease activity (RDA), according to a study. Very low disease activity (VLDA) appears to be the most stringent criterion to identify patients in the absence of RDA.
Obese rheumatoid arthritis (RA) patients taking conventional synthetic (cs-) or biological disease-modifying antirheumatic drugs (DMARDs) see lower rates of disease remission, a recent study has shown.
The association between bronchiectasis and antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) does not appear to be incidental and is mostly correlated with myeloperoxidase (MPO)-ANCA, suggests a recent study.
Patients with hand osteoarthritis (HOA) who have or develop diabetes mellitus (DM) and/or cardiovascular disease (CVD) appear to experience a lower likelihood of symptomatic and functional improvement over time, suggests a study. This indicates the effect of comorbid CVD and DM on the clinical and radiographic course of HOA.
Dr. Hsu Li Yang, Dr. Tan Thuan Tong, Dr. Andrea Kwa,
08 Jan 2021
Antimicrobial resistance has become increasingly dire as the rapid emergence of drug resistance, especially gram-negative pathogens, has outpaced the development of new antibiotics. At a recent virtual symposium, Dr Hsu Li Yang, Vice Dean (Global Health) and Programme Leader (Infectious Diseases), NUS Saw Swee Hock School of Public Health, presented epidemiological data on multidrug-resistant (MDR) gram-negative bacteria (GNB) in Asia, while Dr Tan Thuan Tong, Head and Senior Consultant, Department of Infectious Diseases, Singapore General Hospital (SGH), focused on the role of ceftazidime-avibactam in MDR GNB infections. Dr Andrea Kwa, Assistant Director of Research, Department of Pharmacy, SGH, joined the panel in an interactive fireside chat, to discuss challenges, practical considerations, and solutions in MDR gram-negative infections. This Pfizer-sponsored symposium was chaired by Dr Ng Shin Yi, Head and Senior Consultant of Surgical Intensive Care, SGH.
Spending too much time sitting cannot be good for the body, and rising to one's feet breaks up such a behaviour and yields small, but meaningful, reductions in certain cardiovascular disease (CVD) risk factors, according to the results of a meta-analysis.