Colour duplex sonography may prove useful in diagnosing giant cell arteritis (GCA), providing high specificity and positive predictive value and allowing for a significant reduction in temporal artery biopsies, a study has shown.
Polypharmacy, the prescribing of multiple drugs, in patients with rheumatoid arthritis (RA) appears to be an indicator of comorbidity burden rather than a contributing cause of a drug-related toxicity, a recent study has found, adding that polypharmacy should be monitored to minimize inappropriate combination of prescribed medications.
Long-term use of hydroxychloroquine (HCQ) increases the risk of HCQ retinal toxicity, according to a recent study involving the Korean population. Other risk factors include daily HCQ dose and the presence of kidney disease.
Use of trimethoprim/sulfamethoxazole (TMP-SMX) as primary prophylaxis for pneumocystis pneumonia (PCP) appears to be effective and safe in patients with rheumatic disease receiving prolonged, high-dose steroids, according to a study.
Patients with polymyositis (PM) interstitial lung disease (ILD) vs dermatomyositis (DM)-ILD are more likely to respond to conventional treatment, suggests a recent study. However, clinical characteristics and serology do not otherwise predict response to therapy.
In patients with rheumatoid arthritis (RA) who are also positive for anticitrullinated protein antibodies (ACPA), tocilizumab (TCZ) treatment for 2 years increases femoral neck bone mineral density (BMD) and decreases concentrations of bone resorption markers, a recent study has found.