Interrupting intravenous infusions for at least 4 weeks prior to hip and knee arthroplasty does not improve postoperative outcomes, such as hospitalized infection, prosthetic joint infection and readmission, according to a recent study.
Tacrolimus (TAC) demonstrates noninferior efficacy over leflunomide in the treatment of rheumatoid arthritis patients receiving methotrexate (MTX), with TAC having a reasonable safety profile in those with moderate-to-severe disease activity, according to a study.
Long-term treatment with glucocorticoids (GC) is necessary in polymyalgia rheumatica (PMR), but preliminary data of a study suggests that use of amino bisphosphonates (N-BP) correlates with GC discontinuation in the management of PMR.
Elderly-onset rheumatoid arthritis (EORA) appears to be a risk factor for bone erosions, and not even clinical remission at 1 or 2 years can protect against erosion in anticitrullinated protein autoantibody‐positive EORA patients, a study has reported.
Juvenile idiopathic arthritis in children carries a heightened risk of developing autoimmune diseases—such as rheumatoid arthritis, systemic lupus erythematosus and ankylosing spondylitis, among others—in adulthood, as reported in a recent study.
Eating fish rich in n-3 polyunsaturated fatty acid (PUFA) leads to a lower risk of recurrent gout attacks, a study has found. On the other hand, n-3 PUFA supplements such as fish oil and cod liver oil do not confer the same benefit.
A contraceptive vaginal system (Annovera) releasing a combination of segesterone acetate and ethinyl estradiol (SA/EE) effectively inhibits ovulation up to a year even at low systemic levels of SA, reports a review study presented at ENDO 2019.
Rupatadine at either 10 or 20 mg delivers superior improvements in nasal and ocular symptoms of seasonal allergic rhinitis compared with placebo, with both doses well tolerated by adult and adolescent patients, according to the results of a phase III trial.