The association between bronchiectasis and antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) does not appear to be incidental and is mostly correlated with myeloperoxidase (MPO)-ANCA, suggests a recent study.
Patients with hand osteoarthritis (HOA) who have or develop diabetes mellitus (DM) and/or cardiovascular disease (CVD) appear to experience a lower likelihood of symptomatic and functional improvement over time, suggests a study. This indicates the effect of comorbid CVD and DM on the clinical and radiographic course of HOA.
Dehydroepiandrosterone supplementation confers benefits for quality of life (QoL) but not for disease activity relative to placebo in premenopausal women with rheumatoid arthritis (RA), a study has found.
A growing waistline increases the risk of incident low physical function in the following year among adults with knee osteoarthritis (OA), suggests a recent study. Maintaining waist circumference (WC) may prevent the development of low physical function.
Romilkimab, a novel bispecific immunoglobulin-G4 antibody that binds and neutralizes interleukin (IL)-4/IL-13, shows promise in the treatment of diffuse cutaneous systemic sclerosis, producing significant reduction in skin fibrosis, according to the results of a phase II trial.
Obesity is tied to adverse outcomes in ankylosing spondylitis, including inflammation, disease activity, physical mobility, radiographic damage, health index, liver function, and cardiovascular risk factors, a study suggests.
Higher serum uric acid (UA) levels appear to be protective against vertebral fracture among elderly men, whereas excessive reduction of serum UA using urate-lowering medications confers a risk increase, a study has shown.